Abstract
The Aspirin Myocardial Infarction Study is a randomized, double-blind clinical trial designed to study the potential value of aspirin in the reduction of mortality in patients who have had a prior myocardial infarction. This trial is based upon several previously published studies which suggest that aspirin may be valuable in prevention of coronary thrombosis. The requirement of 4200 patients dictates that the study must be multicenter, and good design requires that the study be collaborative with central monitoring and an elaborate committee structure to insure uniformity and comparability.
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Principal Investigators: Allan H. Barker, David Bayse, David M. Barekson, William H. Bernstein, Nemat O. Borthani, Elmer E. Cooper, Leonard Dreifus, William T. Friedewald, Mario R. Garcia-Palmieri, Sidney Goldstein, Olga M. Haring, J. Joanne Hoover, Richard C. Hutchinson, Kenneth H. Hyatt, William F. Krol, Peter T. Kuo, Charles Laubach, Ralph Lazzara, Bernard I. Lewis, J. Judson McNamara, Jessie Marmorston, Thaddeus E. Prout, David W. Richardson, Jorge Rios, Donald W. Romhilt, Paul Samuel, Stephen Scheidt, Robert Schlant, Henry K. Schoch, James A. Schoenberger, Marvin Segal, C. Basil Williams, Gary N. Wilner, Pantel S. Vokonas.
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The Aspirin Myocardial Infarction Research Group. An intervention study—The aspirin myocardial infarction study. Lipids 12, 59–63 (1977). https://doi.org/10.1007/BF02532973
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DOI: https://doi.org/10.1007/BF02532973