Abstract
Lyme disease is an infectious disease caused by the spirocheteBorrelia burgdorferi. The course of the disease is divided into three stages, the second of which may include various types of peripheral nervous system disturbances. We report the case of a patient with persistent deficits caused by the prevalent involvement of the sciatic nerve, confirmed by electrophysiological and neuropathological findings. The most significant bioptic results were axonal degeneration and perivascular inflammation. Damage to a single peripheral nerve as the dominant clinical expression during the course of Lyme disease is an unusual finding that has been rarely described in the literature.
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References
Dupuis MJM (1988) Les multiples manifestations neurologiques des infections aBorrelia burgdorferi. Rev Neurol 144:765–775
Monteyne P, Dupuis MJM, Sindic CJM (1994) Névrite du grand dentelé associée à une infection parBorrelia burgdorferi. Rev Neurol 150:75–77
Pachner AR, Steere AC (1985) The triad of neurologic manifestations of Lyme disease: Meningitis, cranial neuritis, and radiculo-neuritis. Neurology 35:47–53
Bannwarth A (1941) Chronische lymphocytäre Meningitis entzündliche Polyneuritis und “Rheumatismus”. Ein beitrag zum Problem. Allergie und Nervensystem. Arch Psychiat Nervenkr 113:284–376
Halperin J, Luft BJ, Volkman DJ, Dattwyler RJ (1998) Lyme neuroborreliosis: Peripheral nervous system manifestations. Brain 113:1207–1221
Wulff CH, Hansen K, Strange P, Trojaborg W (1983) Multiple mononeuritis and radiculitis with erythema, pain, elevated CSF protein and pleocytosis (Bannwarth’s syndrome). J Neurol Neurosurg Psychiatry 46:485–490
Hirsch E, Sellal F, Christmann D, Steinmetz G, Monteil H, Jesel M, Warter JM, Collard M (1987) Les méningo-radiculites après morsure de tique: étude de 31 cas. Rev Neurol (Paris) 143:182–188
Vallat JM, Hugon J, Lubeau M, Lebouet MJ, Dumas M, Desproges-Gotteron (1987) Tick-bite meningoradiculoneuritis: Clinical, electrophysiologic, and histologic findings in 10 cases. Neurology (Cleveland) 37:749–753
Kristoferitsch W, Sluga E, Graf M, Partsch H, Neumann R, Stanek G, Budka H (1988) Neuropathy associated with acrodermatitis chronica atrophicans: Clinical and morphological features. Ann N Y Acad Sci 539:35–45
Halperin J, Little BW, Coyle PK, Dattwyler RJ (1987) Lyme disease: Cause of a treatable peripheral neuropathy. Neurology 37:1700–1706
Camponovo F, Meier C (1986) Neuropathy of vasculitic origin in a case of Garin-Bujadoux-Bannwarth syndrome with positive borrelia antibody response. J Neurol 233:69–72
Sterman AB, Neslon S, Barclay P (1982) Demyelinating neuropathy accompanying Lyme disease. Neurology 32:1302–1305
Halperin J, Volkman DJ, Luft BJ, Dattwyler RJ (1989) Carpal tunnel syndrome in Lyme borreliosis. Muscle Nerve 12:397–400
Melet M, Gerard A, Voiriot P, Gayet S, May T, Hermann J, Dournon E, Dureux J, Canton PH (1986) Méningoradiculonevrite mortelle an cours d’une maladie de Lyme. Presse Méd 15:2075
Midgard R, Hofstad H (1987) Unusual manifestations of nervous systemBorrelia burgdorferi infection. Arch Neurol 44:781–783
Baumhackl U, Kristoferitsch W, Sluga E, Stanek G (1986) Neurological manifestations ofBorrelia burgdorferi infections: The enlarging clinical spectrum. Zbl Bakt Hyg 263:334–336
Halperin J, Logigian EL, Finkel MF, Pearl RA (1996) Practice parameters for the diagnosis of patients with nervous system Lyme borreliosis (Lyme disease). Neurology 46:619–627
Garcia-Monco JC, Gomez Beldarrain M, Estrade L (1993) Painful lumbosacral plexitis with increased ESR and Borrelia burgdorferi infection. Neurology 43:1269
Meier C, Grahmann F, Engelhart A, Dumas M (1989) Peripheral nerve disorders in Lyme-Borreliosis. Nerve biopsy studies from eight cases. Acta Neuropathol (Berl) 79:271–278
Tezzon F, Corradini C, Huber R, Egarter Vigl E, Simeoni J, Stanek G, Ferrari G (1991) Vasculitic mononeuritis multiplex in patient with Lyme disease. Ital J Neurol Sci 12:229–232
Maimone D, Villanova M, Stanta G, Bonin S, Malandrini A, Guazzi GC, Annunziata P (1997) Detection ofBorrelia burgdorferi DNA and complement membrane attack com plex deposits in the sural nerve of a patient with chronic polyneuropathy and tertiary Lyme disease. Muscle Nerve 20(8):969–975
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Avanzi, S., Messa, G., Marbini, A. et al. Isolated neuritis of the sciatic nerve in a case of Lyme disease. Ital J Neuro Sci 19, 81–85 (1998). https://doi.org/10.1007/BF02427561
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DOI: https://doi.org/10.1007/BF02427561