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Anabolic steroid therapy as an adjunct to diet in alcoholic hepatic steatosis

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Summary

Nine patients with severe alcoholic fatty livers were studied to evaluate the effects of aqueous testosterone and norethandrolone on the rate of fat removal from the liver. Serial liver biopsies showed that the addition of either of these anabolic steroids to a diet high in calories and protein reversed hepatic steatosis at a rate three to five times faster than that observed with diet alone. The relationship of this therapeutic effect to their actions on serum lipoproteins is discussed, but as yet no definite conclusions can be drawn.

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Authors and Affiliations

  1. From the Division of Gastroenterology, Hepatic Research Laboratory, Indiana University School of Medicine, Indianapolis, Ind.

    Charles L. Mendenhall M.D.

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  1. Charles L. Mendenhall M.D.
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Additional information

Supported in part by Grant PHS AM5223 from the National Institutes of Health, U. S. Public Health Service.

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Mendenhall, C.L. Anabolic steroid therapy as an adjunct to diet in alcoholic hepatic steatosis. Digest Dis Sci 13, 783–791 (1968). https://doi.org/10.1007/BF02233094

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