Abstract
The absorption and metabolism of 2,2-dimethyl-2,3-dihydrobenzofuranyl-7N-dimethoxyphosphinothioyl-N-methylcarbamate (PSC), a selective, insecticidally active carbofuran derivative, was studied in red kidney bean plants. PSC was absorbed from hydroponic culture media and was translocated throughout the plants. PSC was metabolized to carbofuran, 3-hydroxycarbofuran, and 3-ketocarbofuran and these materials accounted for 25% of the recovered radioactivity. Each of these compounds are more toxic to mice than the parent compound. Additionally at least four other oxidized, hydroxylated and/or hydrolyzed metabolites were formed.
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Krieger, R.I., Salhab, A.S., Lee, P.W. et al. Absorption and metabolism of a selective insecticide, 2,2-dimethyl-2,3-dihydrobenzofuranyl-7N-dimethoxyphosphinothioyl-N-Methylcarbamate, in bean plants. Arch. Environ. Contam. Toxicol. 4, 483–491 (1976). https://doi.org/10.1007/BF02221044
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DOI: https://doi.org/10.1007/BF02221044