Conclusions
Providing some simple rules are applied, severe attacks of ulcerative colitis can be effectively managed with virtually no mortality. A proportion of patients (1 in 5) will come to surgery but the guidelines for surgical intervention are now clear. Joint management between medical and surgical teams is important and, possibly, the combination of a surgically aggressive physician with a medicallyminded surgeon is the ideal.
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References
Truelove SC, Witts LJ (1954) Cortisone in ulcerative colitis. Preliminary report on a therapeutic trial. Br Med J 2:375–378
Truelove SC, Witts LJ (1955) Cortisone in ulcerative colitis. Final report on a therapeutic trial. Br Med J 2:1041–1048
Buckell NA, Lennard-Jones JE (1979) How district hospitals see acute colitis. Br Med J iii:1226–1229
Ritchie JK (1974) Results of surgery for inflammatory bowel disease: a further survey of one hospital region. Br Med J i:264–268
Jones HW, Grogono J, Hoare AM (1987) Acute colitis in a district general hospital. Br Med J 294:683–684
Truelove SC, Jewell DP (1974) Intensive intravenous regimen for severe attacks of ulcerative colitis. Lancet 1:1067–1070
Truelove SC, Willoughby CP, Lee EG, Kettlewell MGW (1978) Further experience in the treatment of severe attacks of ulcerative colitis. Lancet ii:1086–1088
Dickinson RJ, Ashton MG, Axon ATR, Smith RC, Yeung CK, Hill GL (1980) Controlled trial of intravenous hyperalimentation and total bowel rest as an adjunct to the routine therapy of acute colitis. Gastroenterology 79:1199–1204
McIntyre PB, Powell-Tuck J, Wood SR, Lennard-Jones JE, Lerebours E, Hecketsweiler P, Galniche JP, Colin R (1986) Controlled trial of bowel rest in the treatment of severe ulcerative colitis. Gut 27:481–485
Baron JH, Connell AM, Kanaghinis TG, Lennard-Jones JE, Jones FA (1962) Outpatient treatment of ulcerative colitis: comparison between three doses of oral prednisolone. Br Med J 2:441–443
Dickinson RJ, O'Connor HJ, Pinder I, Hamilton I, Johnson D, Axon ATR (1985) Double-blind controlled trial of oral vancomycin as adjunctive treatment in acute exacerbations of ulcerative colitis. Gut 26:1380–1384
Chapman RW, Selby WS, Jewell DP (1986) Controlled trial of intravenous metronidazole as an adjunct to corticosteroids in severe ulcerative colitis. Gut 27:1210–1212
Lennard-Jones JE, Ritchie JK, Hilder W, Spicer CC (1975) Assessment of severity in colitis: a preliminary study. Gut 16:579–584
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Jewell, D.P. Medical management of severe ulcerative colitis. Int J Colorect Dis 3, 186–189 (1988). https://doi.org/10.1007/BF01648365
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DOI: https://doi.org/10.1007/BF01648365