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Stimulation of regeneration of joint cartilage by cod liver oil and ASD (3rd fraction)

  • Physiology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Summary

Intracapsular injuries were made in the bone cartilage of the lower epiphysis of the femur. The experiments were performed on 20 dogs aged less than 9 months. It was found that cod liver oil and particularly ASD(3rd fraction) dissolved in cod liver oil had a marked stimulating effect on the regeneration of joint cartilage, but only when the defect extended as far as the spongy substance of the bone. Growth of blood vessels into the clot filling the wound was then accelerated; the resorption of the injured edge of bone cartilage was also intensified, thus favoring the escape of chondrocytes (from the isogenous groups), which later changed into chondroblasts.

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Literature Cited

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Authors and Affiliations

  1. Department of Histology, Stanislavskii Medical Institute, Stanislavskii, USSR

    I. I. Khvorostukhin

Authors
  1. I. I. Khvorostukhin
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Additional information

Translator's note: The abbreviation ASD indicates Dorog's antiseptic stimulator prepared from the decomposition products of microorganic, animal, and plant proteins.

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Khvorostukhin, I.I. Stimulation of regeneration of joint cartilage by cod liver oil and ASD (3rd fraction). Bull Exp Biol Med 52, 1198–1200 (1962). https://doi.org/10.1007/BF00787286

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  • DOI: https://doi.org/10.1007/BF00787286

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