Abstract
The case reports of three patients who received cancer-bearing organs at this institution are presented. A fourth recipient, who was to be transplanted with a cancerous kidney, was spared this disastrous complication. The relevant data regarding the donors is also alluded to, with special reference to the type and site of the primary malignancy. Following these case reports, the implications of these issues, their possible prevention, and further management are discussed.
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Baird RN, White HJO, Tribe CR (1975) Renal carcinoma in a cadaver kidney graft donor. BMJ 2: 371
Baquero A, Foote J, Kottle S, Raja R, Mendez M, Noumoff J, Cavarocchi N, Cohn JB, Bannet AD (1988) Inadvertent transplantation of choriocarcinoma into four recipients. Transplant Proc 20: 98–100
Baquero A, Penn I, Bannet A, Werner DJ, Kim P (1988) Misdiagnosis of metastatic cerebral choriocarcinoma in female cadaver donors. Transplant Proc 20: 776–777
Barnes AD, Fox M (1976) Transplantation of tumor with a kidney graft. BMJ 1: 1442–1444
Couch NP, Curran WJ, Hyg SM, Moore FD (1964) The use of cadaver tissues in transplantation. N Engl J Med 271: 691–695
Finlay IG, McArdle S (1982) The identification of patients at high risk following curative resection for colorectal carcinoma. Br J Surg 69: 583
Fox M (1973) Renal carcinoma in a living kidney graft donor. Transplantation 15: 523–525
Harvey L, Fox M (1981) Transferral of malignancy as a complication of organ transplantation: an insuperable problem? J Clin Pathol 34: 116–122
Jackson AM, Graham DI (1978) Remote metastases from intracranial tumors. J Clin Pathol 31: 794–802
Marsh JW, Esquivel CO, Makowka L, Todo S, Gordon RD, Tzakis A, Miller C, Morris M, Staschak S, Iwatsuki S, Mazariegos J, Kapadia S, Starzl TE (1987) Accidental transplantation of malignant tumor from a donor to multiple recipients. Transplantation 44: 446–450
Martin DC, Rubini M, Rosen VJ (1965) Cadaveric renal homotransplantation with inadvertent transplantation of carcinoma. JAMA 192: 752–754
Matter B, Zukoski CF, Killen DA, Ginn E (1970) Transplanted carcinoma in an immunosuppressed patient. Transplantation 9: 71–74
McCanty TC, Jonsson J, Khawand N, Ali A, Edson M, Light J (1989) Transferral of a malignancy with a transplanted kidney. Transplantation 48: 877–879
Mocelin AJ, Brandino L (1975) Inadvertent transplant of a malignancy. Transplantation 19: 430
Oesterwitz HE, Lucius K (1991) Transmission of cancer with cadaveric donor kidneys. Transplant Proc 23: 2647
Penn I (1986) Transmission of cancer with donor organs. Transplant Proc 18: 471–472
Penn I (1988) Transmission of cancer with donor organs. Transplant Proc 20: 739–740
Penn I (1991) Cancer related to organ transplantation: summary and conclusions. In: Schmahl D, Penn I (eds) Cancer in organ transplant recipients. Springer, Berlin Heidelberg New York, p 179
Starzl TE (1969) Late results and complications. In: Starzl TE (ed) Experience in hepatic transplantation. Saunders, Philadelphia, p 369
Willis RA (1967) Pathology of tumors, 4th edn. Butterworth, London, p 175
Wilson RE, Penn I (1975) Fate of tumors transplanted with a renal allograft. Transplant Proc 7: 327–331
Wilson RE, Hager EB, Hampers CL, Corson JM, Merril JP, Murray JE (1968) Immunologic rejection of human cancer transplanted with a renal allograft. N Engl J Med 278: 479–483
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Detry, O., Detroz, B., D'Silva, M. et al. Misdiagnosed malignancy in transplanted organs. Transpl Int 6, 50–54 (1993). https://doi.org/10.1007/BF00336641
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DOI: https://doi.org/10.1007/BF00336641