Abstract
The effect of five concentrations of mercuric chloride (10 mM, 5 mM, 1 mM, 0.5 mM, and 0.l mM) on the uptake of glucose and fructose from the intestine of the fresh water murrel Channa punctatus after 15, 30 and 60 min was studied. Intestinal glucose and fructose transport was also assessed in fish exposed to a sublethal concentration (3 μg l−1) of mercuric chloride for 10 and 30 days. The results show that the uptake of glucose and fructose from the intestine was reduced by all five concentrations of mercuric chloride. Maximum reduction was observed after 60 min of exposure to 10 mM mercuric chloride. The rate of absorption of glucose and fructose increased with time in controls and in all concentrations of mercury except the highest concentration (10 mM) where the rate of absorption decreased gradually. The reduction in the rate of absorption of the two sugars was not dependent on the concentration of mercury in the instilled medium. In fish exposed to mercuric chloride in laboratory media, the reduction of glucose and fructose absorption was greater after 30 days of exposure than after 10 days.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Alvarado, F.: 1966, Science 151, 1010.
Crane, R. K.: 1962, Fed. Proc. 21, 891.
Crane, R. K., Forstner, G., and Eichholz, A.: 1965, Biochim. Biophys. Acta 109, 467.
Csaky, T. Z.: 1965, Ann. Rev. Physiol. 27, 415.
Formanfarmaian, A.: 1972, Biol.Bull. 142, 247.
Fisher, R. A.: 1950, Statistical Methods for Research Workers, 11th ed. London, Oliver and Boyd.
Lorenz, H.: 1979, Ecotoxicol. Environ. Safety 3, 47.
Miller, D. S., Skehata, A. T., and Lerner, J.: 1980, J. Pharmacol. Exp. Ther. 214, 101.
Musacchia, J. X., and Bramante, A. Y.: 1967, Proceeding of Third International Symposium on Mammalian Hibernation, Edinburgh, Oliver and Boyd.
Nelson, N.: 1944, J. Biol. Chem. 153, 375.
Newcomer, A. D.: 1973, Mayo Clin. Proc. 48, 624.
Official Methods of Analysis.: 1975, Association of Official Analytical Chemists, Washington.
Passow, H., Rothstein, A. and Clarkson, T. W.: 1961, Pharmacol. Rev. 13, 185.
Ponz-Piedrafeta, F., Lluchtrull, M., and Allemany, I.: 1957, Revta. esp. Fisiol. 13, 265.
Rout, W., Lin, D. S. T., and Huang, K. C.: 1965, Proc. Soc. Exp. Biol. 118, 933.
Rothstein, A.: 1962, Circulation 26, 1189.
Sastry, K. V. and Gupta, P. K.: 1978a, Environ. Res. 16, 270.
Sastry, K. V., and Gupta, P. K.: 1978b, J. Environ. Pathol. Toxicol. 2, 443.
Sastry, K. V., and Gupta, P. K.: 1978c, J. Toxicol. Env. Hlth. 4, 777.
Schultz, S. G., Curran, P. F., Chez, R. A., and Fuisz, R. E.: 1967, J. Gen. Physiol. 50, 1241.
Smith, M W.: 1966, J. Physiol. 162, 559.
Smith, R. L., and Lane, C. E.: 1971, Exp. Physiol. Biochem. 4, 93.
Vallee, B. L., and Ulmer, D. D.: 1972, Ann. Rev. Biochem. 41, 91.
Wapnir, R., Moak, S., Lieshitz, F., and Teichberg, S.: 1979, J. Lab. Clin. Med. 94, 144.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Sastry, K.V., Rao, D.R. Mercuric chloride induced alterations in the intestinal transport of glucose and fructose in the fresh water murrel Channa punctatus . Water Air Soil Pollut 19, 143–147 (1983). https://doi.org/10.1007/BF00211800
Received:
Revised:
Issue Date:
DOI: https://doi.org/10.1007/BF00211800