Abstract
Endometriosis is a perplexing disease of unknown etiology and poorly understood histogenesis. It affects women as well as menstruating females of other primate species and is characterized by ectopic i.e., outside of the uterine cavity, growth of endometrium. The growth and spread of endometriosis are controlled by the cyclic stimulation of ovarian hormones. After cessation of ovarian function e.g., during menopause, when ovarian estradiol and progesterone are no longer secreted, uterine as well as ectopic endometria undergo atrophy and endometriosis resolves.
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References
Dmowski, WP (1988). Danazol induced pseudomenopause in the management of endometriosis. In R. Rebar (ed.) Clinical Obstetrics and Gynecology, in press
Meldrum, DR (1985). Clinical management of endometriosis with luteinizing hormone-releasing hormone analogues. Semin Reprod Endocrinol, 3, 371
The American Fertility Society (1985). Revised American fertility society classification of endometriosis. Fertil Steril, 43, 351
Lee, E (1980). “Statistical Methods for Survival Data Analysis.” (Wadsworth, Belmont)
Lemay, A, Maheux, R, Faure, N, Jean, C, and Fazekas, ATA (1984). Reversible hypogonadism induced by a luteinizing hormone-releasing hormone (LH-RH) agonist (Buserelin) as a new therapeutic approach for endometriosis. Fertil Steril, 41, 863
Henig, I, Rawlins, RG, Weinrib, HP and Dmowski, WP (1988). Effects of danazol, gonadotropin releasing hormone agonist and estrogen/progestogen combination on experimental endometriosis in the ovariectomized rat. Fertil Steril, in press
Cann, CE, Henzl, M, Burry, K, Andreko, J, Hanson, F, Adamson, D and Trobough, G (1986). Reversible bone loss is induced by GnRH agonists. Program of the Endocrine Society 68th Annual Meeting, June 25–27, Anaheim, CA
Lewis, V, Ramos, J, and Dawood, MY (1987). Changes in bone mineral content in endometriosis patients treated with GnRH agonist. Program of the Society for Gynecologic Investigation 34th Annual Meeting, March 18–21, Atlanta, GA
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© 1990 Springer Science+Business Media Dordrecht
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Dmowski, W.P., Radwanska, E., Binor, Z., Tummon, I., Pepping, P. (1990). GnRH Agonists in the Management of Endometriosis: The Results of Two Randomized Trials. In: Vickery, B.H., Lunenfeld, B. (eds) GnRH Analogues in Cancer and Human Reproduction. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-2169-6_2
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DOI: https://doi.org/10.1007/978-94-009-2169-6_2
Publisher Name: Springer, Dordrecht
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