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Nonorthopedic or Cardiovascular Implantable Device Infection

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Radionuclide Imaging of Infection and Inflammation
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Abstract

The use of implantable medical devices has increased in “modern” medical and surgical practice [1]. Such devices may be utilized only over a short-time, or intermittently (months/years), or permanently. Their use has frequently been associated with infections [2–4], as the presence of any foreign body significantly increases the risk of infection [5]. The loss of body surface integrity as a consequence of implantable medical devices represents the direct/indirect access of microorganisms [6]. The plastic materials which devices are made of, are easily colonized by either bacteria and/or fungi [7]. Multiresistant nosocomial pathogens are the most common organisms colonizing the surface of catheters where they can proliferate speedily (rate of up to 0.5 cm/hour) [1, 8].

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References

  1. Guggenbichler JP, Assadian O, Boeswald M, Kramer A (2011) Incidence and clinical implication of nosocomial infections associated with implantable biomaterials —catheters, ventilator-associated pneumonia, urinary tract infections. GMS Krankenhhyg Interdiszip 6:Doc18

    Google Scholar 

  2. Vincent JL (2003) Nosocomial infections in adult intensive-care units. Lancet 361:2068–2077

    Article  PubMed  Google Scholar 

  3. National Nosocomial Infections Surveillance System. National Nosocomial Infections Surveillance (NNIS) System Report, data summary from January 1992 to June 2002, issued August 2002 (2002) Am J Infect Control 30:458–475

    Google Scholar 

  4. Safdar N, Crnich CJ, Maki DG (2001) Nosocomial infections in the intensive care unit associated with invasive medical devices. Curr Infect Dis Rep 3:487–495

    Article  PubMed  Google Scholar 

  5. Elek SD, Conen PE (1957) The virulence of Staphylococcus pyogenes for man; a study of the problems of wound infection. Br J Exp Pathol 38:573–586

    PubMed  CAS  Google Scholar 

  6. Lorente L, Henry C, Martin MM, Jiménez A, Mora ML (2005) Central venous catheter-related infection in a prospective and observational study of 2,595 catheters. Crit Care 9:R631–635

    Article  PubMed  Google Scholar 

  7. Locci R, Peters G, Pulverer G (1981) Microbial colonization of prosthetic devices.IV. Scanning electron microscopy of intravenous catheters invaded by yeasts. Zentralbl Bakteriol Mikrobiol Hyg B 173:419–424

    PubMed  CAS  Google Scholar 

  8. Chambless JD, Hunt SM, Stewart PS (2006) A three-dimensional computer model of four hypothetical mechanisms protecting bio-films from antimicrobials. Appl Environ Microbiol 72:2005–2013

    Article  PubMed  CAS  Google Scholar 

  9. Habash M, Reid G (1999) Microbial biofilms: their development and significance for medical-device related infections. J Clin Pharmacol 39:887

    Article  PubMed  CAS  Google Scholar 

  10. Destedt J, Wollin T, Reid G (1998) Biomaterials used in urology: current issues of biocompatibility, infection, and encrustation. J Endourol 12:493–500

    Article  Google Scholar 

  11. Watnick P, Kolter R (dy2000) Biofilm, city of microbes. J Bacteriol 182:2675–2679

    Article  PubMed  CAS  Google Scholar 

  12. Appelgren P, Ransjo U, Bindslev L, Espersen F, Larm O (1996) Surface heparinization of central venous catheters reduces microbial colonization in vitro and in vivo: results from a prospective, randomized trial. Crit Care Med 24:1482–1489

    Article  PubMed  CAS  Google Scholar 

  13. Schembri M, Klemm P (2001) Biofilm formation in a hydrodynamic environment by novel FimH variants and ramifications for virulence. Infect Immun 69:1322–1328

    Article  PubMed  CAS  Google Scholar 

  14. Thomas W, Trintchina E, Forero M, Vogel V, Sokurenko E (2002) Bacterial adhesion to target cells enhanced by shear force. Cell 109:913–923

    Article  PubMed  CAS  Google Scholar 

  15. Donlan R (2001) Biofilm formation: a clinically relevant microbiological process. Clin Infect Dis 33:1387–1392

    Article  PubMed  CAS  Google Scholar 

  16. Costerton J, Stewart P, Greenberg E (1999) Bacterial biofilms: a common cause of persistent infections. Science 284:1318–1322

    Article  PubMed  CAS  Google Scholar 

  17. Mermel LA, Allon M, Bouza E, Craven DE, Flynn P, O’Grady NP et al (2009) IDSA Guidelines for Intravascular Catheter-Related Infection. CID 49:1–45

    Article  CAS  Google Scholar 

  18. Díaz ML, Villanueva A, Herraiz MJ, Noguera JJ, Alonso-Burgos A, Bastarrika G et al (2009) Computed tomographic appearance of chest ports and catheters: a pictorial review for noninterventional radiologists. Curr Probl Diagn Radiol 38:99–110

    Article  PubMed  Google Scholar 

  19. Garner JS, Jarvis WR, Emori TG, Horan TC, Hughes JM (1988) CDC definitions for nosocomial infections. Am J Infect Control 16:128–140

    Article  PubMed  CAS  Google Scholar 

  20. Wakabayashi H, Otani T, Yachida S, Okano K, Izuishi K, Suzuki Y (2006) Central venous catheter-related infection diagnosed by CT. Lancet 368:1466

    Article  PubMed  Google Scholar 

  21. Imataki O, Tamai Y, Watanabe M, Abe Y, Kawakami K (2006) [Central venous catheter-related thrombosis with infection in cancer patients—2 cases]. Gan To Kagaku Ryoho 33:1353–1356

    PubMed  Google Scholar 

  22. Ito I, Miura A (2011) [A case of type 2 diabetes mellitus complicated with left iliopsoas abscess caused by a left femoral vein catheter during treatment for right pyothorax and right subphrenic abscess]. Nihon Ronen Igakkai Zasshi 48:180–184

    Article  PubMed  Google Scholar 

  23. Cook RJ, Ashton RW, Aughenbaugh GL, Ryu JH (2005) Septic pulmonary embolism: presenting features and clinical course of 14 patients. Chest 128:162–166

    Article  PubMed  Google Scholar 

  24. Gutfilen B, Lopes de Souza SA, Martins FP, Cardoso LR, Pinheiro Pessoa MC, Fonseca LM (2006) Use of 99mTc-mononuclear leukocyte scintigraphy in nosocomial fever. Acta Radiol 47:699–704

    Article  PubMed  CAS  Google Scholar 

  25. Lai CH, Chi CY, Chen HP, Lai CJ, Fung CP, Liu CY (2004) Port-A catheter-associated Nocardia bacteremia detected by gallium inflammation scan: a case report and literature review. Scand J Infect Dis 36:775–777

    PubMed  Google Scholar 

  26. Miller JH (1981) Detection of deep venous thrombophlebitis by gallium 67 scintigraphy. Radiology 140:183–186

    PubMed  CAS  Google Scholar 

  27. Chiu J-S, Tzeng J-E, Wang Y-F (2006) Infection hunter: gallium scintigraphy for hemodialysis access graft infection. Kidney International 69:1290

    Article  PubMed  Google Scholar 

  28. Sullivan SJ, Quadri SM, Cunha BA (1992) Hickman catheter Staphylococcus aureus bacteremia diagnosed by indium-111 scan. Heart Lung 21:505–506

    PubMed  CAS  Google Scholar 

  29. Bhargava P, Kumar R, Zhuang H, Charron M, Alavi A (2004) Catheter-related focal FDG activity on whole body PET imaging. Clinical Nuclear Medicine 29:238–242

    Article  PubMed  Google Scholar 

  30. Mahfouz T, Miceli MH, Saghafifar F, Stroud S, Jones-Jackson L, Walker R et al (2005) 18F-fluorodeoxyglucose positron emission tomography contributes to the diagnosis and management of infections in patients with multiple myeloma: a study of 165 infectious episodes. J Clin Oncol 23:7857–7863

    Article  PubMed  CAS  Google Scholar 

  31. Miceli MH, Jones-Jackson LB, Walker RC, Talamo G, Barlogie B, Anaissie EJ (2004) Diagnosis of infection of implantable central venous catheters by [18F]fluorodeoxyglucose positron emission tomography. Nuclear Med Comm 25:813–818

    Article  Google Scholar 

  32. Stenehjem E, Armstrong WS (2012) Central nervous system device infections. Infect Dis Clin N Am 26:89–110

    Article  Google Scholar 

  33. Stoodley P, Braxton EE Jr, Nistico L, Hall-Stoodley L, Johnson S, Quigley M et al (2010) Direct demonstration of Staphylococcus biofilm in an external ventricular drain in a patient with a history of recurrent ventriculoperitoneal shunt failure. Pediatr Neurosurg 46:127–132

    Article  PubMed  Google Scholar 

  34. Medina M, Viglietti AL, Gozzoli L, Lucano A, Ravasi L, Lucignani G et al (2000) Indium-111 labelled white blood cell scintigraphy in cranial and spinal septic lesions. Eur J Nucl Med 27:1473–1480

    Article  PubMed  CAS  Google Scholar 

  35. Liberatore M, Drudi FM, Tarantino R, Prosperi D, Fiore V, Missori P et al (2003) Tc-99m exametazime-labeled leukocyte scans in the study of infections in skull neurosurgery. Clin Nucl Med 28:971–974

    Article  PubMed  Google Scholar 

  36. Wan DQ, Joseph UA, Barron BJ, Caram P, Nguyen AP et al (2009) Ventriculoperitoneal shunt catheter and cerebral spinal fluid infection initially detected by FDG PET/CT scan. Clin Nucl Med 34:464–465

    Article  PubMed  Google Scholar 

  37. Rehman T, Chohan M, Yonas H (2011) Diagnosis of ventriculoperitoneal shunt infection using [F-18]-FDG PET: a case report. J Neurosurg Sci 55:161–163

    PubMed  CAS  Google Scholar 

  38. Hamani C and Lozano AM (2006) Hardware-related complications of deep brain stimulation: a review of the published literature. Stereotact Funct Neurosurg 84:248–251

    Article  PubMed  Google Scholar 

  39. Real R, Linhares P, Fernandes H, Rosas MJ, Gago MF, Pereira J et al (2011) Role of 99mTc-sulesomab immunoscintigraphy in the management of infection following deep brain stimulation surgery. Neurology Res Int 2011:Article ID 817951, 8 pages. doi:10.1155/2011/817951

    Google Scholar 

  40. Wilson SK, Costerton JW (2012) Biofilm and penile prosthesis infections in the era of coated implants: a review. J Sex Med 9:44–53

    Article  PubMed  Google Scholar 

  41. Moncada I, Jara J, Cabello R, Monzo JI and Hernández C (2004) Radiological assessment of penile prosthesis: the role of magnetic resonance imaging. World J Urol (2004) 22: 371–377

    Article  PubMed  Google Scholar 

  42. Better N, Ahn CS, Drum DE, Tow DE (1994) Identification of penile prosthetic infection on 67gallium scan. J Urol 152:475–476

    PubMed  CAS  Google Scholar 

  43. Achong D, Zloty M (2008) In-111 WBC scintigraphy for evaluation of the painful penile prosthesis. J Nucl Med 49:266P

    Google Scholar 

  44. Spear SL, Seruya M (2010) Management of the Infected or Exposed Breast Prosthesis: A Single Surgeon’s 15-Year Experience with 69 Patients. Plast Reconstr Surg 125:1074–1084

    Article  PubMed  CAS  Google Scholar 

  45. Pittet B, Montandon D, Pittet D (2005) Infection in breast implants. Lancet Infect Dis 5:94–106

    PubMed  Google Scholar 

  46. Brand KG (1993) Infection of mammary prostheses: a survey and the question of prevention. Ann Plast Surg 30:289–95

    Article  PubMed  CAS  Google Scholar 

  47. De Cholnoky T (1970) Augmentation mammaplasty. Survey of complications in 10,941 patients by 265 surgeons. Plast Reconstr Surg 45:573–77

    Article  PubMed  Google Scholar 

  48. Ahn CY, Ko CY, Wagar EA, Wong RS, Shaw WW (1996) Microbial evaluation: 139 implants removed from symptomatic patients. Plast Reconstr Surg; 98:1225–29

    Article  PubMed  CAS  Google Scholar 

  49. Macadam SA, Mehling BM, Fanning A et al. (2007) Nontuberculous mycobacterial breast implant infections. Plast Reconstr Surg. 119:337–44

    Article  PubMed  CAS  Google Scholar 

  50. Walsh R, Kliewer MA, Sullivan DC et al. (1995) Periprosthetic mycobacterial infection. CT and mammographic findings. Clin Imaging 19:193–6

    Article  PubMed  CAS  Google Scholar 

  51. Dessy LA, Corrias F, Marchetti F et al. (2012) Implant infection after augmentation mammaplasty: a review of the literature and report of a multidrug-resistant Candida albicans infection. Aesth Plast Surg 36:153–159

    Article  Google Scholar 

  52. Van Wingerden JJ, van Staden MM (1989) Ultrasound mammography in prostheses-related breast augmentation complications. Ann Plast Surg 22:32–35

    Article  PubMed  Google Scholar 

  53. Khedher NB, David J, Trop I, Drouin S, Peloquin L, Lalonde L (2011) Imaging findings of breast augmentation with injected hydrophilic polyacrylamide gel: Patient reports and literature review. Eur J Radio 178:104–111

    Article  Google Scholar 

  54. Lee CJ, Kim SG, Kim L, Choi MS, Lee SI (2004) Unfavorable findings following breast augmentation using injected polyacrylamide hydrogel. Plast Reconstr Surg 114:1967–1968

    Article  PubMed  Google Scholar 

  55. Lui CY, Ho CM, Iu PP et al (2008) Evaluation of MRI findings after polyacrylamide gel injection for breast augmentation. AJR Am J Roentgenol 191:677–688

    Article  PubMed  Google Scholar 

  56. Leslie K, Buscombe J, Davenport A (2000) Implant infection in a transsexual with renal failure. Nephrol. Dial. Transplant 15:436–437

    CAS  Google Scholar 

  57. Ellenberger P, Graham WP 3rd, Manders EK, Basarab RM (1986) Labeled leukocyte scans for detection of retained polyurethane foam. Plast Reconstr Surg 77:77–79

    Article  PubMed  CAS  Google Scholar 

  58. Chen CJ, Lee BF, Yao WJ et al (2009) A false positive 18F-FDG PET/CT scan caused by breast silicone injection. Korean J Radiol 10:194–196

    Article  PubMed  Google Scholar 

  59. Bakheet SM, Powe J, Kandil A, Ezzat A, Rostom A, Amartey J (2000) F-18 FDG uptake in breast infection and inflammation. Clin Nucl Med 25:100–103

    Article  PubMed  CAS  Google Scholar 

  60. Adejolu M, Huo L, Rohren E, Santiago L, Yang WT (2012) False-positive lesions mimicking breast cancer on FDG PET and PET/ CT. AJR Am J Roentgenol. 198:W304–14

    Article  PubMed  Google Scholar 

  61. Lim HS, Yoon W, Chung TW et al (2007) FDG PET/CT for the detection and evaluation of breast diseases: usefulness and limitations. Radiographics. 27:S197–213

    Article  PubMed  Google Scholar 

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Erba, P.A. (2013). Nonorthopedic or Cardiovascular Implantable Device Infection. In: Radionuclide Imaging of Infection and Inflammation. Springer, Milano. https://doi.org/10.1007/978-88-470-2763-3_6

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  • DOI: https://doi.org/10.1007/978-88-470-2763-3_6

  • Publisher Name: Springer, Milano

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  • Online ISBN: 978-88-470-2763-3

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