Skip to main content
SpringerLink
Log in

Nuclear Medicine Imaging of Abdominal Infections and Inflammation

  • Chapter
Radionuclide Imaging of Infection and Inflammation

Abstract

Several different clinical entities can cause abdominal infections/inflammatory diseases and they usually present with general symptoms such as abdominal pain, general discomfort, fever and diarrhea. In the assessment of acute abdominal pain, the main diagnostic tests remain radiologic and endoscopic investigation, but also nuclear medicine has a role in the management of such patients. Some of the several pathologies causing abdominal inflammation/infections can be studied with nuclear medicine non-invasive techniques and there are different radionuclides that can be helpful to the physician in the management, from diagnosis to therapy follow-up, of patients with abdominal infections or inflammatory diseases. Unfortunately, it is remarkable that most of the nuclear medicine examinations are not able to give a quick diagnosis in acute abdominal pain with signs of perforation and therefore are not first line examinations.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 129.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Krukowski ZH, Matheson NA (1988) Ten-year computerized audit of infection after abdominal surgery. Br J Surg 75:857–861

    Article  PubMed  CAS  Google Scholar 

  2. Weiss G, Meyer F, Lippert H (2006) Infectiological diagnostic problems in tertiary peritonitis. Langenbecks Arch Surg 391:437–482

    Article  Google Scholar 

  3. Solomkin JS, Mazuski JE, Baron EJ et al (2003) Guidelines for the selection of anti-infective agents for complicated intra-abdominal infections. Clin Infect Dis 37:997–1005

    Article  PubMed  Google Scholar 

  4. Cheadle WG, Spain DA (2003) The continuing challenge of intra-abdominal infection. Am J Surg 186:15S–22S

    Article  PubMed  Google Scholar 

  5. Christou NV, Barie PS, Dellinger EP et al (1993) Surgical Infection Society intra-abdominal infection study. Prospective evaluation and management techniques and outcome. Arch Surg 128:193–198

    Article  PubMed  CAS  Google Scholar 

  6. Bohnen J, Boulanger M, Meakins JL, et al (1983) Prognosis in generalized peritonitis. Relation to cause and risk factors. Arch Surg 118:285–290

    Article  PubMed  CAS  Google Scholar 

  7. Mazuski JE, Sawyer RG, Nathens AB, et al (2002) The Surgical Infection Society guidelines on antimicrobial therapy for intra-abdominal infections: Evidence for the recommendations. Surg Infect (Larchmt) 3:175–233

    Article  Google Scholar 

  8. Solomkin JS, Mazuski JE, Bradley JS, Rodvold KA, Goldstein EJC, Baron EJ et al (2010) Diagnosis and management of complicated intra-abdominal infection in adults and children: Guidelines by the Surgical Infection Society and the Infectious Diseases Society of America. Complicated intra-abdominal infection guidelines. Clin Infect Dis 50:133–164

    Article  PubMed  Google Scholar 

  9. Ogawa S, Itabashi M, Kameoka S (2009) Significance of FDG-PET in identification of diseases of the appendix-based on experience of two cases falsely positive for FDG accumulation. Case Rep Gastroenterol 3:125–130

    Article  PubMed  Google Scholar 

  10. Koff SG, Sterbis JR, Davison JM, Montilla-Soler JL (2006) A unique presentation of appendicitis: F-18 FDG PET/CT. Clin Nucl Med 31:704–706

    Article  PubMed  Google Scholar 

  11. Tahara T, Ichiya Y, Kuwabara Y, Otsuka M, Miyake Y, Gunasekera R, Masuda K (1989) High [18F]-fluorodeoxyglucose uptake in abdominal abscesses: a PET study. J Comput Assist Tomogr 13:829–831

    Article  PubMed  CAS  Google Scholar 

  12. Annovazzi A, Bagni B, Burroni L, D’Alessandria C, Signore A (2005) Nuclear medicine imaging of inflammatory/infective disorders of the abdomen. Nucl Med Commun 26:657–664

    Article  PubMed  Google Scholar 

  13. Peacock K, Porn U, Howman-Giles R, O’Loughlin E, Uren R, Gaskin K et al (2004) 99mTc-stannous colloid white cell scintigraphy in childhood inflammatory bowel disease. J Nucl Med 45:261–265

    PubMed  Google Scholar 

  14. de Groot M, Meeuwis AP, Kok PJ, Corstens FH, Oyen WJ (2005) Influence of blood glucose level, age and fasting period on non-pathological FDG uptake in heart and gut. Eur J Nucl Med Mol Imaging 32:98–101

    Article  PubMed  Google Scholar 

  15. Toriihara A, Yoshida K, Umehara I, Shibuya H (2011) Normal variants of bowel FDG uptake in dual-time-point PET/CT imaging. Ann Nucl Med 25:173–178

    Article  PubMed  Google Scholar 

  16. Karczmarczyk U, Garnuszek P, Maurin M, Di Gialleonardo V, Galli F, Signore A et al (2010) Investigation of 99mTc-labeling of recombinant human interleukin-2 via hydrazine-nicotinamide. Nucl Med Biol 37:795–803

    Article  PubMed  CAS  Google Scholar 

  17. Signore A, Chianelli M, Annovazzi A, Bonanno E, Spagnoli L, Pozzilli P et al (2000) 123I-interleukin-2 scintigraphy for the in vivo assessment of intestinal mononuclear cell infiltration in Crohn’s disease. J Nucl Med 41:242–249

    PubMed  CAS  Google Scholar 

  18. Annovazzi A, Biancone L, Caviglia R, Chianelli M, Capriotti G, Mather SJ et al (2003) 99mTc-interleukin-2 and (99m)Tc-HMPAO granulocyte scintigraphy in patients with inactive Crohn’s disease. Eur J Nucl Med Mol Imaging 30:374–382

    Article  PubMed  CAS  Google Scholar 

  19. D’Alessandria C, Malviya G, Viscido A, Aratari A, Maccioni F, Amato A et al (2007) Use of a99mTc labeled anti-TNFalpha monoclonal antibody in Crohn’s disease: in vitro and in vivo studies. Q J Nucl Med Mol Imaging 51:334–342

    PubMed  Google Scholar 

  20. Versari et al (2007) FDG-PET in idiopathic retroperitoneal fibrosis. J Nucl Med 48 (Supplement 2):288P

    Google Scholar 

  21. Cobb WS, Carbonell AM, Kalbaugh CL et al (2009) Infection risk of open placement of intraperitoneal composite mesh. Am Surg 75:762–768

    PubMed  Google Scholar 

  22. Vix J, Meyer C, Rohr S et al (1997) The treatment of incisional and abdominal hernia with a prosthesis in potentially infected tissues: a series of 47 cases. Hernia 1:157–161

    Article  Google Scholar 

  23. Petersen S, Henke G, Freitag M et al (2001) Deep prosthesis infection in incisional hernia repair: Predictive factors and clinical outcome. Eur J Surg 167:453–457

    Article  PubMed  CAS  Google Scholar 

  24. Eriksen JR, Gogenur T, Rosenberg J (2007) Choice of Mesh for laparoscopic ventral hernia repair. Hernia 11:481–492

    Article  PubMed  CAS  Google Scholar 

  25. Sanchez VM, Abi-Haider YE, Itani KMF (2011) mesh infection in ventral incisional hernia repair: incidence, contributing factors, and treatment. Surg Infect 12:205–210

    Article  Google Scholar 

  26. Zuvela M, Antic A, Bajec D, Radenkovic D, Petrovic M, Galun D et al (2011) Diagnosis of mesh infection after abdominal wall hernia surgery-role of radionuclide methods. Hepatogastroenterology 58:1455–1460

    Article  PubMed  Google Scholar 

  27. Lin WY, Chao TH, Wang SJ (2002) Clinical features and gallium scan in the detection of post-surgical infection in the elderly. Eur J Nucl Med Mol Imaging 29:371–375

    Article  PubMed  Google Scholar 

  28. Datz FL (1996) Abdominal abscess detection: gallium, 111In-, and 99mTc-labeled leukocytes, and polyclonal and monoclonal antibodies. Semin Nucl Med 26:51–64

    Article  PubMed  CAS  Google Scholar 

  29. Palestro CJ, Love C, Tronco GG, Tomas MB (2000) Role of radionuclide imaging in the diagnosis of postoperative infection. Radio-graphics 20:1649–1660

    CAS  Google Scholar 

  30. Thodis E, Passadakis P, Lyrantzopooulos N, Panagoutsos S, Vargemezis V, Oreopoulos D (2005) Peritoneal catheters and related infections. Int Urol Nephrol 37:379–393

    Article  PubMed  Google Scholar 

  31. Vargemezis V (2001) Prevention and management of peritonitis and exit-site infection in patients on continuous ambulatory peritoneal dialysis. Nephrol Dial Transplant 16:106–168

    Article  PubMed  Google Scholar 

  32. Quantrill SJ, Woodhead MA, Bell CE, Hutchison AJ, Gokal R (2001) Peritoneal tuberculosis in patients receiving continuous ambulatory peritoneal dialysis. Nephrol Dial Transplant 16:1024–1027

    Article  PubMed  CAS  Google Scholar 

  33. Stuart et al (2009) Complications of continuous ambulatory peritoneal dialysis. Radiographics 29:441–460

    Article  PubMed  Google Scholar 

  34. Sheikh M, Abu-Zidan F, al-Hilaly M, Behbehani A (1995) Abdominal tuberculosis: comparison of sonography and computed tomography. J Clin Ultrasound 23:413–417

    Article  PubMed  CAS  Google Scholar 

  35. Kipper SL, Steiner RW,WilztumKF et al (1984) In-111 leukocyte scintigraphy for detection of infection associated with peritoneal dialysis catheters. Radiology 151:491–494

    PubMed  CAS  Google Scholar 

  36. Ruiz Solis S, Garcia Vicente A, Rodaco Marina S et al (2004) Diagnosis of the infectious complications of continuous ambulatory peritoneal dialysis by 99mTc-HMPAO labeled leucocytes [Spanish]. Rev Esp Med Nucl 23:403–413

    Article  Google Scholar 

  37. Gibel LJ, Hartshorne MF, Tzamaloukas AH (1998) Indium-111 oxine leukocyte scan in the diagnosis of peritoneal catheter tunnel infections. Perit Dial Int 18:234–235

    PubMed  CAS  Google Scholar 

  38. Ruiz Solis S, Garcia Vicente A, Rodaco Marina S et al (2004) Diagnosis of the infectious complications of continuous ambulatory peritoneal dialysis by 99mTc-HMPAO labeled leucocytes [Spanish]. Rev Esp Med Nucl 23:403–413

    Article  Google Scholar 

  39. Gibel LJ, Quintana BJ, Tzamaloukas AH, Garcia DL (1989) Soft tissue complications of Tenckhoff catheters. Adv Perit Dial 5:229–233

    PubMed  CAS  Google Scholar 

  40. Carlos MG, Juliana R, Matilde N et al (2008) Hidden clotted vascular access infection diagnosed by fluorodeoxyglucose positron emission tomography. Nephrology (Carlton) 13:264–265

    Article  Google Scholar 

  41. Singh P, Wiggins B, Sun Y, Servilla KS, Last RE, Hartshorne MF et al (2010) Imaging of peritoneal catheter tunnel infection using positron-emission tomography. Adv Perit Dial 26:96–100

    PubMed  Google Scholar 

  42. de Lima Ramos PA, Martín-Comín J, Prats E et al (1998) Scintigraphic assessment of the severity of inflammatory bowel disease using Tc 99m exametazime-labeled leukocytes Rev Esp Med Nucl 17:351–7

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Nuclear Medicine, Department of Surgery and Translational Medicine, University of Rome “La Sapienza” S. Andrea Hospital, Rome, Italy

    Alberto Signore

Authors
  1. Alberto Signore
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

Copyright information

© 2013 Springer-Verlag Italia

About this chapter

Cite this chapter

Signore, A. (2013). Nuclear Medicine Imaging of Abdominal Infections and Inflammation. In: Radionuclide Imaging of Infection and Inflammation. Springer, Milano. https://doi.org/10.1007/978-88-470-2763-3_10

Download citation

  • DOI: https://doi.org/10.1007/978-88-470-2763-3_10

  • Publisher Name: Springer, Milano

  • Print ISBN: 978-88-470-2762-6

  • Online ISBN: 978-88-470-2763-3

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation