Abstract
In 2001, in the United States, there were approximately 17,200 new diagnoses of cancers of “the brain and other nervous systems”, with 13,100 consequent cancer-related deaths [1]. Men were affected more often that women in the ratio of 1.3:1. In the adult, metastases were several times more frequent than primary tumors [2, 3]. Primary tumors of the central nervous system (CNS) make up about 1.5% of all cancers and 2.5% of all cancer-related deaths [4]. Spinal cord tumors, both primary and metastatic, are about 10% as frequent as cerebral tumors [5]. Although the incidence of primary CNS tumors increases with increasing age, these tumors are proportionately more frequent in childhood [6], when primary CNS tumors are the most frequent solid cancers, with an incidence of 2–3 per 100,000 and are the second most frequent cause of cancer-related deaths [6, 7]. The most frequent primary tumors in children are medulloblastoma and low-grade astrocytoma [6].
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Parker, R.G., Janjan, N.A., Selch, M.T. (2003). Malignant Tumors of the Central Nervous System. In: Radiation Oncology for Cure and Palliation. Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-05225-9_14
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