Abstract
Sjögren’s syndrome (SS) is a chronic autoimmune disease of unknown aetiology, characterized by lymphocyte infiltration of exocrine glands resulting in xerostomia and keratoconjunctivitis sicca. In more than one third of patients, extraglandular manifestations, such as skin, lung, kidney, liver, muscle and blood vessel involvement can occur. SS can be found alone (primary SS) or in association with other autoimmune diseases, such as rheumatoid arthritis, systemic lupus erythematosus, sclerodermia, (secondary SS) for example. Five percent of patients may develop B cell lymphoma.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Talai N, Moutsopoulos HM, Kassan SS (1987) Sjögren’s syndrome Clinical and Immunological aspects. Springer, Berlin
Fox PC, Atkinson JC, Maynski AA et al (1991) Pilocarpine treatment of salivary gland hypofunction and dry mouth (xerostomia). Arch Intern Med 151: 1149–1152
Moutsopoulos HM (1994) Sjögren’s syndrome–autoimmune epithelitis. Clin Immunol Immunopathol 72: 162–165
Moutsopoulos HM, Velthuis PI, De Wide PCM, Kater L (1995) Sjögren’s syndrome. In: Kater L, de la Faille HB (eds) Multisystemic Autoimmune diseases. Elsevier Science BV, Amsterdam, pp 173–205
Haneji N, Nakamura T, Takiok et al (1997) Identification of a fodrin as a candidate autoantigen in primary Sjögren’s syndrome. Science 276: 604–607
Tzioufas AG, Moutsopoulos HM (1993) Sjögren’s syndrome. In: Klippel JH, Dieppe PA (eds) Rheumatology. Mosby, London 6:32. 1–12
Vlachoyiannopoulos PG, Moutsopoulos HM (1998) Therapy of Sjögren’s syndrome. In: van de Putte LBA, Furst DE, WilliamsHJ, van Riel PLCM (eds) Therapy of systemic rheumatic disorders. Marcel Dekker, New York, pp 615–628
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2000 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Tzioufas, A.G., Moutsopoulos, H.M. (2000). Sjögren’s Syndrome. In: Katsambas, A.D., Lotti, T.M. (eds) European Handbook of Dermatological Treatments. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-03835-2_91
Download citation
DOI: https://doi.org/10.1007/978-3-662-03835-2_91
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-662-03837-6
Online ISBN: 978-3-662-03835-2
eBook Packages: Springer Book Archive