Abstract
In 1956 Della Porta et al. [3] and Shubik et al. [13] reported the interesting finding that multiple melanotic tumours develop in a large proportion of hamsters painted with chemical carcinogens. As is well known, other animals produce mainly epithelial tumours under these conditions. Working on the hypothesis that this difference might be due to some anatomical peculiarity in hamster skin, we proceeded to study it by various methods, and discovered the small pigmented spots from which these melanomas arise [7].
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Similar content being viewed by others
References
Ahavoni, B.: Die Muriden von Palästina und Syrien. Z. Säugetierk. 7, 166 bis 240 (1932).
Berenblum, I., Nechama, Haran-Ghera, and N. Trainin: An experimental analysis of hair cycle effect in mouse skin carcinogenesis. Brit. J. Cancer 12, 402–413 (1958).
Della Porta, G., H. Rappaport, U. Saffiotti, and P. Shubik: Induction of melanotic lesions during skin carcinogenesis in hamsters. Arch. Path. 61, 305–313 (1956).
Ghadially, F. N.: Comparative morphological study of kerato-acanthoma of man and similar experimentally produced lesions in rabbit. J. Path. Bact. 75, 441–453 (1958).
Ghadially, F. N.: Experimental production of kerato-acanthomas in hamster and mouse. J. Path. Bact. 77, 277–282 (1959).
Ghadially, F. N.: The role of the hair follicle in the origin and evolution of some cutaneous neoplasms of man and experimental animals. Cancer 14, 801–816 (1961).
Ghadially, F. N., and J. F. Barker: The histogenesis of experimentally induced melanotic tumours in the Syrian hamster (Cricetus auratus). J. Path. Bact. 79, 263–271 (1960).
Ghadially, F. N., and O. Illman: The histogenesis of experimentally produced melanotic tumours in the Chinese hamster, (Cricetulus criseus). Brit. J. Cancer 17, 727–730 (1964).
Illman, O., and F. N. Ghadially: Coat colour and experimental melanotic tumour production in the hamster. Brit. J. Cancer 14, 483–488 (1960).
Quevedo, W. C., J. M. Cairns, Jean A. Smith, F. G. Bocx, and R. J. Burns: Induction of melanotic tumours in the white (partial albino) Syrian hamster. Nature 189, 836–837 (1961).
Rappaport, H., G. Pietra, and P. Shubik: The induction of melanotic tumours resembling cellular blue nevi in the Syrian white hamster by cutaneous application of 7,12-dimethylbenz(a)anthracene. Cancer Res. 21, 661–666 (1961).
Simpson, W. L., and W. Cramer: Fluorescence studies of carcinogens in skin; 1. histological localisation of 20-methylcholanthrene in mouse skin after single application. Cancer Res. 3, 362–369 (1943).
Shubik, P., G. Della Porta, H. Rappaport, and Kathryne Spencer: Atransplantable induced melanotic tumor of the Syrian golden hamster. Cancer Res. 16, 1031–1032 (1956).
Suntzeff, V., E. V. Cowdry, and A. Croninger: Microscopic visualization of degeneration of sebaceous glands caused by carcinogens. Cancer Res. 15, 637–640 (1955).
Waterhouse, C. R.: Description of a new species of hamster (Cricetus auratus). Proc. Zool. Soc. Lond. 7, 57–58 (1839).
Willis, R. A.: Pathology of tumours, pp. 108, 204. London: Butterworth 1960.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1966 Springer-Verlag Berlin · Heidelberg
About this paper
Cite this paper
Ghadially, F.N., Illman, O. (1966). Small Pigmented Spots in Hamsters. In: Porta, G.D., Mühlbock, O. (eds) Structure and Control of the Melanocyte. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-99906-2_30
Download citation
DOI: https://doi.org/10.1007/978-3-642-99906-2_30
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-99908-6
Online ISBN: 978-3-642-99906-2
eBook Packages: Springer Book Archive