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Adenocarcinoma, Glandular Stomach, Rat

  • Chapter
Digestive System

Part of the book series: Monographs on Pathology of Laboratory Animals ((LABORATORY))

Abstract

Most cases of experimentally induced adenocarcinoma arise in the antral region, in the vicinity of the pylorus of the glandular stomach. In early cases the tumors appear as round or oval, slightly elevated solitary or multiple lesions 2–4 mm in diameter (Fig. 283). Some cases of intramucosal carcinoma with erosion, located in the level of the mucous membrane, have also been observed. The mean diameter of advanced carcinomas is 5–6 mm (Ohgaki et al. 1983), but tumors 20–30 mm in diameter have also been found. Macroscopically three different types can be distinguished: umbilicated or ulcerated tumors with irregular elevated margins; flowerbed-like lesions with a central area of depression; hemispherical or polypous protruded lesions (Saito et al. 1970).

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Authors
  1. Zoltán Szentirmay
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  2. János Sugar
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Editors and Affiliations

  1. New England Regional Primate Research Center, Harvard Medical School, One Pine Hill Drive, Southborough, MA, 01772, USA

    Thomas Carlyle Jones D.V.M., D.Sc. (Professor of Comparative Pathology, Emeritus) & Ronald Duncan Hunt D.V.M. (Professor of Comparative Pathology) (Professor of Comparative Pathology, Emeritus) &  (Professor of Comparative Pathology)

  2. Institut für Experimentelle Pathologie, Medizinische Hochschule Hannover, Konstanty-Gutschow-Strasse 8, 3000, Hannover 61, Federal Republic of Germany

    Ulrich Mohr M. D. (Professor of Experimental Pathology) (Professor of Experimental Pathology)

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© 1985 Springer-Verlag Berlin Heidelberg

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Szentirmay, Z., Sugar, J. (1985). Adenocarcinoma, Glandular Stomach, Rat. In: Jones, T.C., Mohr, U., Hunt, R.D. (eds) Digestive System. Monographs on Pathology of Laboratory Animals. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-96910-2_53

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  • DOI: https://doi.org/10.1007/978-3-642-96910-2_53

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-96912-6

  • Online ISBN: 978-3-642-96910-2

  • eBook Packages: Springer Book Archive

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