Abstract
Nerve growth factor (NGF) is indispensable for the correct functioning of the sympathetic and sensorial autonomic nervous system, with multiple effects and potential clinical applications, specifically in Alzheimer’s disease [2]. We are not aware of a specific active trophic factor on the motor system, analogous to the NGF, which would correspond to a muscle-derived protein [5, 6]. The “target- derived” trophism is an aspect of the autonomic system which is still under discussion. At the present time, it is believed that the NGF is synthesized by glial cells, astrcytes, and laminine [7]. The aim of this study is tu use the facial nerve, which is a mixed nerve, like the sciatic nerve and the trigeminal nerve [1], and to evaluate the possible effect of NGF on all its fibers.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Davies AM (1990) NGF synthesis and NGF receptor expression in the embryonic mouse trigeminal system. J Physiol (Paris) 84: 100–103
Hefti F, Schneider LS (1991) Nerve growth factor and Alzheimer’s disease. Clin Neuropharmacol 14 [Suppl 1]: 562–576
Poduslo JF (1985) Regulation of myelinatin Schwann cell transition from a myelin-maintaining state to a quiescent state after permanent nerve transection. J Neurochem 44: 388–400
Schawab ME, Thoenen H (1985) Nerve growth factor. Its action modes. J Neurosci 5: 2415–2423
Seckel BR (1990) Enhancement of peripheral nerve regeneration. Muscle Nerve 13: 785–800
Slack JR, Hopkins WG, Pockett S (1983) Evidence for a motor nerve growth factor. Muscle Nerve 6: 243–252
Varon S, Adler R (1981) Trophic and specifying factors directed to neuronal cells. Adv Cell Neurobiol 2: 115–163
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1994 Springer-Verlag
About this paper
Cite this paper
Bernardo, M.J., Ablanedo, P., Suarez, C., Alvarez-Uria, M., Llorente, J.L. (1994). Nerve Growth Factor: Morphological and Morphometric Findings on Facial Nerve Regeneration in the Rabbit. In: Stennert, E.R., Kreutzberg, G.W., Michel, O., Jungehülsing, M. (eds) The Facial Nerve. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-85090-5_155
Download citation
DOI: https://doi.org/10.1007/978-3-642-85090-5_155
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-57686-0
Online ISBN: 978-3-642-85090-5
eBook Packages: Springer Book Archive