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Applications of Magnetic Resonance Spectroscopy to Nutrition and Metabolism

  • Chapter
Metabolic Support of the Critically Ill Patient

Part of the book series: Update in Intensive Care and Emergency Medicine ((UICM,volume 17))

Abstract

The development of magnetic resonance spectroscopy (MRS) has made it possible to examine cellular and organellar function non-invasively and to improve our understanding of the pathophysiological and clinical changes observed in many disease states. Various MRS techniques allow investigators to study intracellular abnormalities, their biochemical bases, and the mechanisms by which they occur. These responses are important to understand since they often antedate the development of more overt manifestations of disease and end-state organ failure. Organ systems that have been studied include muscle, heart, brain, and liver.

“Disease can impose an extreme short term disturbance, which leads to a regulatory catastrophe, or instability of metabolic control, in individual cells, whole organs, or the total organism. All these processes and phenomena have their molecular basis in the underlying biochemical events that are functionally expressed only in the living cells or organisms.”[1, 2]

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Authors
  1. D. O. Jacobs
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  2. M. K. Robinson
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Editor information

Editors and Affiliations

  1. Laboratory for Surgical Metabolism, Brigham and Women’s Hospital, 75 Francis Street, Boston, Massachussetts, 02115, USA

    Douglas W. Wilmore

  2. L. Deloyers Laboratory for Experimental Surgery, Free University of Brussels, Avenue J. Wybran 40, 1070, Brussels, Belgium

    Yvon A. Carpentier

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© 1993 Springer-Verlag Berlin Heidelberg

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Jacobs, D.O., Robinson, M.K. (1993). Applications of Magnetic Resonance Spectroscopy to Nutrition and Metabolism. In: Wilmore, D.W., Carpentier, Y.A. (eds) Metabolic Support of the Critically Ill Patient. Update in Intensive Care and Emergency Medicine, vol 17. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-85011-0_2

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  • DOI: https://doi.org/10.1007/978-3-642-85011-0_2

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-85013-4

  • Online ISBN: 978-3-642-85011-0

  • eBook Packages: Springer Book Archive

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