Abstract
Local hyperthermia (HT) has been demonstrated to be an effective adjunct to ionizing radiation (RT) in cancer therapy. Several clinical trials employing RT plus HT (Overgaard 1984) have shown that HT can improve local control rates of both primary and recurrent tumors. However, the precise role of some hyperthermia parameters in clinical RT and HT studies is still not well defined. In an attempt to substantiate and clarify the results of our previous experience with different numbers of heat sessions (Valdagni et al. 1986 a), a randomized clinical trial for N3 neck nodes (UICC 1973) comparing radical irradiation plus two heat treatments versus radical irradiation plus six heat sessions was activated in September 1985. This study is part of a randomized protocol comparing radical irradiation alone versus radical irradiation plus heat (Valdagni et al. 1986 b).
This work was partly supported by Provincia Autonoma di Trento and Fondazione per La Ricerca sul Cancro “L. Pece”.
The author wishes to thank Dr. Fei Fei Liu for reviewing the manuscript and Drs. M. Amichetti and G. Pani for their helpful clinical collaboration. He also thanks Marge Keskin for skillful secretarial assistance.
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© 1988 Springer-Verlag Berlin · Heidelberg
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Valdagni, R. (1988). Two Versus Six Hyperthermia Treatments in Combination with Radical Irradiation for Fixed Metastatic Neck Nodes: Progress Report. In: Issels, R.D., Wilmanns, W. (eds) Application of Hyperthermia in the Treatment of Cancer. Recent Results in Cancer Research, vol 107. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-83260-4_17
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DOI: https://doi.org/10.1007/978-3-642-83260-4_17
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