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Acute Lymphoblastic Leukemia: Current Status of Therapy in Children

  • Chapter
Leukemia

Part of the book series: Recent Results in Cancer Research ((RECENTCANCER,volume 93))

Abstract

The symptoms of acute lymphoblastic leukemia (ALL) — pallor, bleeding, and infection or erythro-, thrombo-, and granulocytopenia — are due to the massive accumulation of undifferentiated cells in the bone marrow. The purpose of therapy, therefore, is to eradicate these leukemic cells in all body compartments. Prolonged disease-free survival (and subsequent cure) depends on the rapidity and thoroughness of cytoreduction. Thus, curative efforts have evolved to their present form as aggressive combination chemotherapy.

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  1. Universitäts-Kinderpoliklinik, Feulgenstrasse 12, 6300, Giessen, Germany

    F. Lampert, G. Henze, H.-J. Langermann, G. Schellong, H. Gadner & H.-J. Riehm

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  1. Institut für Hämatologie, Abteilung für Immunologie, Gesellschaft für Strahlen- und Umweltforschung mbH, Landwehrstrasse 61, 8000, München 2, Germany

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Lampert, F., Henze, G., Langermann, HJ., Schellong, G., Gadner, H., Riehm, HJ. (1984). Acute Lymphoblastic Leukemia: Current Status of Therapy in Children. In: Thiel, E., Thierfelder, S. (eds) Leukemia. Recent Results in Cancer Research, vol 93. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-82249-0_6

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  • DOI: https://doi.org/10.1007/978-3-642-82249-0_6

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