Abstract
Over the past 60 years a considerable amount of information has been amassed concerning the role of viruses in naturally occurring cancers. In particular, the group of viruses known as the RNA tumor viruses has been implicated in a variety of cancers in a wide spectrum of animals. In addition to the presence of the virus, numerous genetic, hormonal, and environmental factors play an important permissive role in the development of many neoplasias. Although the presence of RNA tumor viruses in humans or their involvement in human cancer remains as yet unproven, information from experimental systems is clearly consistent with this possibility. Recent advances in molecular and cell biology and immunology have been applied to the search for a human virus. These studies have provided evidence for the possible presence of these viruses in human tumors. In this presentation we would like to review the recent evidence concerning the unique biologic characteristics of the RNA tumor viruses as well as the methods currently being utilized in attempts to detect their presence in experimental animal and human systems. Consideration will also be given to the relevance of these findings to the human breast cancer problem.
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Schochetman, G., Schlom, J. (1976). RNA Tumor Viruses and Breast Cancer. In: St-Arneault, G., Band, P., Israël, L. (eds) Breast Cancer. Recent Results in Cancer Research / Fortschritte der Krebsforschung / Progrès dans les recherches sur le cancer, vol 57. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-81043-5_3
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DOI: https://doi.org/10.1007/978-3-642-81043-5_3
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