Abstract
Research on human beings is important and necessary for the common good of society. Human experimentation is essential for the expansion of scientific knowledge in order to prevent, treat and cure disease. Despite the value of medical research in saving lives and relieving pain, the use of humans for experimental purposes often meets with opposition [1]. Medical progress requires clinical trials to introduce beneficial treatments and prevent the introduction of non-useful or harmful therapies. It would be helpful if the lay public became aware of the importance of clinical trials and became more knowledgeable about them before they were asked to participate in them. In 1747, one of the earliest reported clinical trials was performed by Sir James Lind in sailors with scurvy [2]. The first randomized controlled trial in modern times which occurred after World War II was the treatment of pulmonary tuberculosis with streptomycin [3]. There are those who believe that experimentation on human beings takes place continually in every doctor’s office and that deliberate experimentation on a group of patients is merely an efficient way to collect and interpret data that would otherwise be lost [1]. Some physicians believe all therapies should be given as part of clinical trials. Clearly, modern clinical investigations are different than research done in the past.
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Sprung, C.L., Eidelman, L.A., Nyman, D.J. (1995). Ethical Issues in Clinical Trials. In: Vincent, JL., Sibbald, W.J. (eds) Clinical Trials for the Treatment of Sepsis. Update in Intensive Care and Emergency Medicine, vol 19. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-79224-3_25
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DOI: https://doi.org/10.1007/978-3-642-79224-3_25
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