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Abstract

Classically the autonomic nervous system consists of two components, cholinergic and adrenergic nerves; the former are contained mostly in the parasympathetic, and the latter mostly in the sympathetic division. For the past 4 decades a third component of the autonomic system, which is neither cholinergic nor adrenergic, has been recogized; the principal active substance released from these nerves in the gastrointestinal tract is a purine nucleotide; they have been called purigenic nerves by Burnstock (1972). An increasing number of peptides with a dual localization in endocrine cells and peripheral nerves in the walls of the gastrointestinal tract has now been recognized. This has led to the concept of a three-part autonomic control system consisting of cholinergic, adrenergic and peptidergic nerves (Bishop et al. 1977).

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© 1993 Springer-Verlag Berlin Heidelberg

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Keet, A.D. (1993). Nerves. In: The Pyloric Sphincteric Cylinder in Health and Disease. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-77708-0_8

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  • DOI: https://doi.org/10.1007/978-3-642-77708-0_8

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-77710-3

  • Online ISBN: 978-3-642-77708-0

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