Abstract
Malignant melanoma represents about 5% of skin cancers and 2% of malignant tumors (excluding the other skin cancers). Its incidence is extremely variable and is evaluated at 0.3/100000 inhabitants in Japan and up to 40/100000 inhabitants in Queensland, Australia, a number which is considered the highest in the world.
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References
Ackerman LV, Del Regato JA (1962) Malignant melanoma of the skin. In: Cancer: diagnosis, treatment, and prognosis. Mosby -cV, St Louis
Aigner KR, Hüd P, Hundeiker M (1981) Neue Entwicklungen in der isolierten Extremitäten Perfusion. Z Hautkr 57:1044–1054
Aigner KR, Walther H, Link KH, Voigt H (1986) Perfusionstherapie. In: Voigt H, Kleeber UR (eds) Malignes Melanom. Springer, Berlin Heidelberg New York, pp 299–305
Bulman AS, Jamieson CW (1980) Isolated limb perfusion with melphalan in the treatment of malignant melanoma. Br J Surg 67: 660–662
Cavalière R, Ciocatto E, Giovanella B, Heidelberger C, Johnson R, Magottini M, Mondovi B, Moricca G, Rossi-Favelli A (1967) Selective heat sensitivity of cancer cells. Biochemical and clinical studies. Cancer 20:1351–1381
Creech O, Krementz ET, Ryan RF, Winblad JN (1958) Chemotherapy of cancer: regional perfusion utilizing an extracorporeal circuit. Ann Surg 148:616–632
Cruchley PM, Kaplan JA, Waller JL, Youg MR (1982) Anesthesia for isolated hyperthermic limb perfusion. Anesthesiology 57:228–230
Cumberlin R, De Moss E, Lassus M, Freidman M (1985) Isolation perfusion for malignant melanoma of the extremity: a review. J Clin Oncol 3:1022–1031
Davis CD, Ivins JC, Soule EH (1976) Mayo Clinic experience with isolated limb perfusion for invasive malignant melanoma of the extremities. Proceedings of the ninth international pigment cell conference, Houston Texas. In: Riley R (ed) Pigment cell. Karger S, New York, pp 379–385
De Cosse JJ, Rogers LS (1966) Influence of high pressure oxygen and chemotherapy of the A. Mel 4 hamster melanoma. Cancer Res pt 1:287–292
Didolkar MS, Fitzpatrick JL, Jackson AJ, Johnson GS (1986) Toxicity and complications of vascular isolation and hyperthermic perfusion with imidazole carboxamide in melanoma. Cancer 57:1961–1966
Fletcher JR, White CR, Fletcher WA (1986) Improved survival rates of patients with acral lentiginous melanoma treated with hyperthermic isolation perfusion, wide excision, and regional lymphadenectomy. Am J Surg 151:593–597
Fontijne WPJ, Mook PH, Schraffordt-Koops J, Oldhoff J, Wildevuur RH (1985) Improved tissue perfusion during pressure regulated hyperthermic regional isolated perfusion. A clinical study. Cancer 55:1455–1461
Ghussen F, Nagel K, Groth W (1981) Regionale hyper-therme Zytostatikaperfusion bei malignen Melanomen der Extremitäten. Dtsch Med Wochenschr 106:1612–1615
Ghussen F, Nagel K, Groth W, Müller JM, Stützer H (1984) A prospective randomized study of regional extremity perfusion in patients with malignant melanoma. Ann Surg 200:764–768
Ghussen F, Kruger I, Groth W, Stützer H (1986) Randomized melanoma study of perfusion of the extremities. Results of treatment 21/2 years after premature discontinuation. Chirurg 57:619–623
Ghussen F, Kruger I, Groth W, Stützer H (1988) The role of regional hyperthermic cytostatic perfusion in the treatment of extremity melanoma. Cancer 61:654–659
Golomb FM, Bromberg J, Dubin N (1979) A controlled study of the survival experience of patients with primary malignant melanoma of the distal extremities treated with adjuvant isolated perfusion. Adjuvant Ther Cancer 2:519–526
Gundersen S, Hager B, Tausjo J (1986) Radiation in combination with intra-arterial infusion therapy with dacarbazine for metastatic malignant melanoma localized to a lower extremity. Cancer Treat Rev 70:1015–1017
Janoff KA, Moseson D, Nohlgren J, Davenport C, Richards C, Fletcher WS (1982) The treatment of stage I melanoma of the extremities with regional hyperthermic isolation perfusion. Ann Surg 196:316–323
Klein ES, Ben-Ari GY (1987) Isolation perfusion with cis-platin for malignant melanoma of the limbs. Cancer 59:1068–1071
Klopp C, Alford T, Bateman J, Berry G, Winship T (1950) Fractionated intra-arterial cancer chemotherapy with methyl bis amine hydrochloride. A preliminary report. Ann Surg 132:811–832
Krementz ET (1986) Regional perfusion. Current sophistication, what next? Cancer 57:426–432
Krementz ET, Knudson L (1961) The effect of increased oxygen tension on the tumoricidal effect of nitrogen mustard. Surgery 50:266–271
Krementz ET, Ryan RF (1972) Chemotherapy of melanoma of the extremities by perfusion; fourteen years clinical experience. Ann Surg 175:900–917
Krementz ET, Carter RD, Sutherland CM, Campbell M (1979) The use of regional chemotherapy in the management of malignant melanoma. World J Surg 3:289–304
Krementz ET, Carter RD, Sutherland CM, Muchmore JH (1987) Chemotherapy by regional perfusion for limb melanoma. Am Surg 53:133–140
Lee YTNM (1980) Loco-regional recurrent melanoma. I. Natural history. Cancer Treat Rev 7:59–72
Lejeune F, Achten G (1983) Le mélanome malin cutané. Stratégies et résultats thérapeutiques. In: Le mélanome malin. XVIIe congrès de l’association des dermatologistes et syphiligraphes de langue française. Brussels, June 2–4, pp 249–291
Luck J (1956) Action of p-[di(2-chloroethylamino-L-phenylalanine] on Harding Passey mouse melanoma. Science 123:984–985
Martijn H, Olkhoff J, Schraffordt-Koops H, Oosterhuis J (1982) Hyperthermic regional perfusion with melphalan and a combination of melphalan and actinomycin D in the treatment of locally metastasized malignant melanoma of the extremities. J Surg Oncol 20:9–13
Martijn H, Oldhoff J, Oosterhuis JW, Schraffordt-Koops H (1983) Indications for elective groin dissection in clinical stage I patients with malignant melanoma of the lower extremity treated by hyperthermic regional perfusion. Cancer 52:1526–1534
Martijn H, Schraffordt-Koops H, Milton GW, Nap M, Oosterhuis JW, Shaw HM, Oldhoff J (1986) Comparison of two methods of treating primary malignant melanomas Clark IV et V, thickness 1.5 mm and greater localized on the extremities. Cancer 57:1923–1930
McBride CM, Sugarbaker EV, Hickey RC (1975) Prophylactic isolation perfusion as the primary therapy for invasive malignant melanoma of the limbs. Ann Surg 182:316–324
Millar RD, Ketcham AS (1974) The effect of heparin and warfarin on primary and metastatic tumors. J Med 5:23–31
Minor DR, Allen RE, Alberts D, Peng YM, Tardellin G, Hutchinson J (1985) A clinical and pharmacokinetic study of isolated limb perfusion with heat and melphalan for melanoma. Cancer 55:2638–2644
Nachbur B (1986) Die Perfusionsbehandlung des Extremitä-tenmelanomas. Indikationen, Technik, Komplikationen und Ergebnisse der regionalen Perfusionsbehandlung des malignen Melanomas der Extremitäten. Huber, Bern, p 104
Rampen FHJ (1985) Towards a rational perfusion strategy for malignant melanoma. Eur J Surg Oncol 11:117–118
Schraffordt-Koops H, Oldhoff J, Oosterhuis JW, Beekhuis H (1985) The role of isolated limb perfusion for regional metastases of the extremities. In: Balch CM (ed) Surgical approaches to cutaneous melanoma. Karger, Basel, pp 146–164 (Pigment Cell, vol 7.)
Shingleton WW, Seigler HF, Stocks LH, Downs RW (1975) Management of recurrent melanoma of the extremity. Cancer 35:574–579
Shiu MH, Knapper WH, Fortner JG, Yeh S, Horowitz G, Schnog J, Guerra J, Gould-Rossbach P, Ray C (1986) Regional isolated limb perfusion of melanoma in transit metastases using mechlorethamine (nitrogen mustard). J Clin Oncol 4:1819–1826
Stehlin JS (1969) Hyperthermic perfusion with chemotherapy for cancers of the extremity. Surg Gynecol Obstet 129:305–308
Stehlin JS, Giovanella BC, De Ipolyi PD, Muenz LR, Anderson RF (1975) Results of hyperthermic perfusion for melanoma of the extremities. Surg Gynecol Obstet 140:339–348
Storm FK, Morton DL (1985) Value of therapeutic hyperthermic limb perfusion in advanced recurrent melanoma of the lower extremity. Am J Surg 150:32–35
Storm FK, Silberman AW, Ramming KR, Kaiser LR, Harrison WH, Elliott RS, Haskell CM, Sarna G, Morton DL (1984) Clinical thermochemotherapy. A controlled trial in advanced cancer patients. Cancer 53:863–868
Sugarbaker ER, McBride CM (1976) Survival and regional disease control after isolation perfusion for invasive stage I melanoma of the extremities. Cancer 37:188–198
Sutherland CM, Mather FJ, Krementz ET (1987) Factors influencing the survival of patients with regional melanoma of the extremity treated by perfusion. Surg Gynecol Obstet 164:111–118
Tonak J, Hermanek P, Banz H, Groitl H (1979) Cytotoxics and hyperthermic perfusion: a preliminary study. Cancer Treat Rev 6:135–141
Tonak J, Hohenbergen W, Göhl J (1984) Die isolierte hyper-therme Extremitätenperfusion bei malignen Melanomen und Weichgewebssarkomen. Chirurg 55:499–504
Van OS J, Schraffordt-Koops H, Oldhoff J (1985) Dosimetry of cytostatics in hyperthermic regional isolated perfusion. Cancer 55:698–701
Wagner DE (1976) A retrospective study of regional perfusion for melanoma. Arch Surg 111:410–413
Wieberding J, Benckhuysen C, Braat RP, Van Slooten EA, Olthuis GAA (1982) Dosimetry in isolation perfusion of the limbs by assessment of perfused tissue volume and grading of toxic tissue reactions. Eur J Cancer Clin Oncol 18:905–910
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Truchetet, F., Grosshans, E., Kretz, J.C., Friedel, J., Chartier, C. (1990). Combined Hyperthermia and Chemotherapy for Malignant Melanoma of the Limbs. In: Gautherie, M. (eds) Interstitial, Endocavitary and Perfusional Hyperthermia. Clinical Thermology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74640-6_4
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DOI: https://doi.org/10.1007/978-3-642-74640-6_4
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