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Treatment of Chronic Myelogenous Leukemia with Interferons: Hematologic, Cellular, and Genetic Investigations

  • Conference paper
Modern Trends in Human Leukemia VIII

Part of the book series: Haematology and Blood Transfusion / Hämatologie und Bluttransfusion ((HAEMATOLOGY,volume 32))

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Abstract

Chronic myelogenous leukemia (CML) is a stem cell disorder characterized by the accumulation of immature precursors of the granulocytic and monocytic lineage. Most commonly, the disease is treated with chemotherapeutic agents, preferably busulfan and hydroxyurea. High-dose chemotherapy followed by allogeneic bone marrow transplantation may eradicate the malignant clone and offers the possibility of cure [1, 2].

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Author information

Authors and Affiliations

  1. Institute for Molecular Biology, University of Essen (GHS), Hufelandstr. 55, D-43, Essen 1, Germany

    B. Opalka

  2. Department of Internal Medicine, University of Essen (GHS), Hufelandstr. 55, D-43, Essen 1, Germany

    O. Kloke, U. Wandl, R. Becher & N. Niederle

Authors
  1. B. Opalka
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  2. O. Kloke
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  3. U. Wandl
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  4. R. Becher
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  5. N. Niederle
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Editor information

Editors and Affiliations

  1. Medizinische Klinik, Abteilung für klinische Chemie, Universitäts-Krankenhaus Eppendorf, Martinistraße 52, 2000, Hamburg 20, Germany

    Rolf Neth

  2. Laboratory of Tumor Cell Biology, National Cancer Institute, 20892, Bethesda, MD, USA

    Robert C. Gallo

  3. Chester Beatty Laboratories, Leukemia Research Fund Centre, Institute of Cancer Research, Fulham Road, London, SW3 6JB, UK

    Melvyn F. Greaves

  4. Abteilung Pädiatrie II, Universitätskinderklinik und Poliklinik Ulm, Prittwitzstr. 43, 7900, Ulm, Germany

    Gerhard Gaedicke

  5. Universität Ulm, Prittwitzstr. 43, 7900, Ulm, Germany

    Gerhard Gaedicke

  6. Labor für Hautimmunologie, Bioverträglichkeit-Immunologie, Paul-Gerson-Unna-Forschungszentrum, Beiersdorf-AG, Unnastr. 48, 2000, Hamburg 20, Germany

    Sven Gohla

  7. Heinrich-Pette-Institut für Experimentelle Virologie und Immunologie, Martinistr. 52, 2000, Hamburg 20, Germany

    Klaus Mannweiler

  8. Abteilung Hämatologie und Onkologie, Kinderklinik und Poliklinik der Westfälischen Wilhelms-Universität, Albert-Schweitzer-Str. 33, 4400, Münster, Germany

    Jörg Ritter

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© 1989 Springer-Verlag Berlin Heidelberg

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Opalka, B., Kloke, O., Wandl, U., Becher, R., Niederle, N. (1989). Treatment of Chronic Myelogenous Leukemia with Interferons: Hematologic, Cellular, and Genetic Investigations. In: Neth, R., et al. Modern Trends in Human Leukemia VIII. Haematology and Blood Transfusion / Hämatologie und Bluttransfusion, vol 32. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74621-5_23

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  • DOI: https://doi.org/10.1007/978-3-642-74621-5_23

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-50967-7

  • Online ISBN: 978-3-642-74621-5

  • eBook Packages: Springer Book Archive

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