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Neuropsychiatric Illness and Deficiency of Vitamin B12 and Folate

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Folates and Cobalamins

Abstract

Deficiency of either folate or vitamin B12 (cobalamin) causes megaloblastic anemia. Reports that folate supplements might aggravate the neurological defects in deficiency of vitamin B12 were interpreted during the 1970s to suggest that folate deficiency did not induce neurological abnormality [47]. This is consistent with the observation that the various neurological and psychiatric abnormalities reported in patients deficient in folate could not be readily demonstraded as secondary to the folate deficiency [43].

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Authors
  1. M. I. Botez
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Editors and Affiliations

  1. Division d’Hématologie et d’Oncologie médicale, Hôpital Royal Victoria et Département de Médecine interne et de Physiologie, Université McGill, Montréal, Québec, Canada

    Bernard A. Cooper

  2. Laboratoire d’Hématologie, Hôpital Henri Mondor et Faculté de Médecine, 94010, Créteil, France

    Jacqueline A. Zittoun

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Botez, M.I. (1989). Neuropsychiatric Illness and Deficiency of Vitamin B12 and Folate. In: Cooper, B.A., Zittoun, J.A. (eds) Folates and Cobalamins. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74364-1_11

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  • DOI: https://doi.org/10.1007/978-3-642-74364-1_11

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