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Expression of Differentiation Antigens on Blast Cells of Acute Myelogenous Leukemia (AML, M0–M6)

  • Conference paper
Acute Leukemias VII

Part of the book series: Haematology and Blood Transfusion / Hämatologie und Bluttransfusion ((HAEMATOLOGY,volume 39))

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Abstract

Forty one patients with AML (M01 4 patients, M11 5, M21 7, M41 8, M5a1 16, and M61 one patient) have been studied. Cytochemical reactions (MPO, CAE, AcP, ANAE, NE, PAS) and immunological detection of antigens expression (indirect immunoperoxidase, APAAP methods and, in some cases, flow cytometry) were performed. The definition of typical phenotypical pattern for discrete FAB-variants AML was carried out. Significant heterogeneity of monoblasts was revealed. Cases of AML, M5a with unusual phenotypical features were discovered. Its origin from hierarchy of hematopoietic stem cells is discussed.

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Authors
  1. I. Abramenko
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  2. D. Gluzman
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  3. N. Bilous
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  4. V. Chromyak
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  5. L. Sklyarenko
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  6. S. Andreeva
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Editor information

Editors and Affiliations

  1. Department of Internal Medicine, University of Göttingen, Robert-Koch-Straße 40, 37075, Göttingen, Germany

    W. Hiddemann  & B. Wörmann  & 

  2. Department of Internal Medicine, USA

    T. Büchner

  3. Department of Pediatrics, University of Münster, Albert-Schweitzer-Straße 33, 48149, Münster, Germany

    J. Ritter  & U. Creutzig  & 

  4. Dept. of Hematology, University of Texas, Anderson Cancer Center, 1515 Holcombe Boulevard, 77030, Houston, Tx., USA

    M. Keating MD PhD  & W. Plunkett MD PhD  & 

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© 1998 Springer-Verlag Berlin Heidelberg

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Abramenko, I., Gluzman, D., Bilous, N., Chromyak, V., Sklyarenko, L., Andreeva, S. (1998). Expression of Differentiation Antigens on Blast Cells of Acute Myelogenous Leukemia (AML, M0–M6). In: Hiddemann, W., et al. Acute Leukemias VII. Haematology and Blood Transfusion / Hämatologie und Bluttransfusion, vol 39. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71960-8_6

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  • DOI: https://doi.org/10.1007/978-3-642-71960-8_6

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-71962-2

  • Online ISBN: 978-3-642-71960-8

  • eBook Packages: Springer Book Archive

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