Abstract
The identification and interpretation of brain damage resulting from a non-missile head injury is often not easy — if only because the most obvious structural damage identified post mortem may not be the most important. There must be many occasions when death is certified as being due to fracture of the skull and cerebral contusions when neither may have even been the reason for the patient having been unconscious. Patients with a fracture and quite severe contusions can make an uneventful and complete recovery from their injury if no other types of brain damage are present (cf. Figs. 7 and 9). The aim of this chapter therefore is to advise on a pragmatic approach to the autopsy, to define clearly the various types of brain damage that may occur, and to remind the pathologist that he must know what he is looking for. This is particularly important when there is no evidence of severe cerebral contusions or of a large intracranial haematoma. A patient may die as a result of a non-missile head injury without either of these being present. Thus a systematic approach is required, and the pathologist must be aware of the more subtle — and often most important — types of brain damage that can occur in a patient who sustains a non-missile head injury. Frequently the damage can be identified only microscopically.
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References
Adams JH, Mitchell DE, Graham DI, Doyle D (1977) Diffuse brain damage of immediate impact type. Brain 100:489–502
Adams JH, Murray MF (1982) Atlas of post mortem techniques in neuropathology. Cambridge University Press, Cambridge
Adams JH, Gennarelli TA, Graham DI (1982a) Brain damage in nonmissile head injury: observations in man and subhuman primates. In: Smith WT, Cavanagh JB (eds) Recent advances in neuropath-ology, II. Churchill Livingstone, London, p 165
Adams JH, Graham DI, Murray LS, Scott G (1982b) Diffuse axonal injury due to non-missile head injury in humans: an analysis of 45 cases. Ann Neurol 12:557–563
Adams JH, Graham DI (1984) Diffuse brain damage in non-missile head injury. In: Anthony PP, MacSween RNM (eds) Recent advances in histopathology, 12. Churchill Livingstone, Edinburgh, p241
Adams JH, Doyle D, Graham DI, Lawrence AE, McLellan DR, Gennarelli TA, Pastuszko M, Sakamoto T (1985) The contusion index: a reappraisal in human and experimental non-missile head injury. Neuropathol Appl Neurobiol 11:299–308
Adams JH, Doyle D, Graham DI, Lawrence AE, McLellan DR (1986 a) Gliding contusions in non-missile head injury in humans. Arch Pathol Lab Med 110:485–488
Adams JH, Doyle D, Graham DI, Lawrence AE, McLellan DR (1986b) Deep intracerebral (’basal ganglia’) haematomas in fatal nonmissile head injury in man. J Neurol Neurosurg Psychiat 49: 1039–1043
Gennarelli TA, Thibault LE, Adams JH, Graham DI, Thompson CJ, Marcincin RP (1982) Diffuse axonal injury and traumatic coma in the primate. Ann Neurol 12: 564–574
Graham DI, Adams JH, Doyle D (1978) Ischaemic brain damage in fatal non-missile head injuries. J Neurol Sci 39: 213–234
Lindenberg R, Freytag E (1960) The mechanism of cerebral contusions. Arch Pathol Lab Med 69: 440–469
McLellan DR, Adams JH, Graham DI, Kerr AE, Teasdale GM (1986) The structural basis of the vegetative state and prolonged coma after non-missile head injury. In: Papo I, Cohadon F, Massarotti M (eds) Le coma traumatique. Liviana Editrice, Padova, Italy
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© 1988 Springer-Verlag Berlin Heidelberg
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Adams, J.H. (1988). The Autopsy in Fatal Non-Missile Head Injuries. In: Berry, C.L. (eds) Neuropathology. Current Topics in Pathology, vol 76. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71353-8_1
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DOI: https://doi.org/10.1007/978-3-642-71353-8_1
Publisher Name: Springer, Berlin, Heidelberg
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