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The Effects of Intra-Carotid Artery Administration of Mannitol on Cerebral Blood Flow and Intracranial Pressure in Experimental Brain Edema

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Intracranial Pressure

Abstract

Brain edema following head injury is considered to be a major factor in the generation of the subsequent increase in intracranial pressure (ICP). Moderate brain edema can still be controlled in many cases by various techniques such as hyperventilation, administration of hyperosmotic drugs and steroids, and internal or external decompression of the brain, but severe brain edema is untreatable in most cases.

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References

  1. Betz, E., Ingvar, D. H., Lassen, N. A., Schmahl, F. W.: Regional blood flow in the cerebral cortex, measured simultaneously by heat and inert gas clearance. Acta physiol. scand. 67, 1–9 (1966).

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  2. Aviram, A., Pfau, A., Czaczkes, J. W., Ulman, T. D.: Hyperosmolality with hyponatremia, caused by inappropriate administration of mannitol. Amer. J. Med. 42, 648–650 (1967).

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© 1972 Springer-Verlag Berlin

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Shalit, M.N. (1972). The Effects of Intra-Carotid Artery Administration of Mannitol on Cerebral Blood Flow and Intracranial Pressure in Experimental Brain Edema. In: Brock, M., Dietz, H. (eds) Intracranial Pressure. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-65486-2_29

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  • DOI: https://doi.org/10.1007/978-3-642-65486-2_29

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-65488-6

  • Online ISBN: 978-3-642-65486-2

  • eBook Packages: Springer Book Archive

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