Abstract
According to the WHO Histological Classification of Thyroid Tumours (Hedinger et al. 1988), malignant tumours arising from the follicular epithelium of the thyroid are histologically classified as papillary carcinoma, follicular carcinoma or undifferentiated (anaplastic) carcinoma. The clinical and biological behaviour of papillary and follicular carcinoma are clearly different from that of undifferentiated carcinoma (Donohue et al. 1984; Franssila 1973). The first two have a better prognosis, while the latter usually leads to a poor outcome. Both structural and cellular atypia are prominent in undifferentiated carcinoma compared to those in follicular and papillary carcinoma.
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Sakamoto, A. (1997). Poorly Differentiated Carcinoma of the Thyroid: An Aggressive Type of Tumour Arising from Thyroid Follicular Epithelium. In: Schmid, K.W., Böcker, W. (eds) Thyroid Pathology. Current Topics in Pathology, vol 91. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-60531-4_5
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DOI: https://doi.org/10.1007/978-3-642-60531-4_5
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