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Laparoscopic Staging for Pancreatic Malignancy

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Staging Laparoscopy

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Abstract

Pancreatic cancer is an uncommon malignancy with an unfavorable prognosis that occurs predominantly in the sixth and seventh decades of life. Adenocarcinoma is the most common histological type of this disease and will occur in more than 80% of patients with pancreatic cancer. At the time of diagnosis only 10% of patients have disease confined to the pancreas, 40% exhibit local spread, and 50% demonstrate distant disease (metastatic) spread [1, 2].

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References

  1. Brennan MF, Kinsella TJ, Casper ES (1993) Cancer of the Pancreas. In: DeVita VT, Hellman S, Rosenberg SA (eds) Principles and practice of oncology, 5th ed. J.B. Lippincott, Philadelphia, pp 849–882

    Google Scholar 

  2. Carter D (1990) Cancer of the Pancreas. Gut 31:494–496

    Article  PubMed  CAS  Google Scholar 

  3. Geer R, Brennan M (1993) Resection of Pancreatic Adenocarcinoma: Prognostic Indicators for Survival. Am J Surg 223:279

    Google Scholar 

  4. Harrison LE, Brennan MF (1997) Portal vein involvement in pancreatic cancer: a sign of unresectability? Adv Surg 31:375–394

    PubMed  CAS  Google Scholar 

  5. Fernandez-del Castillo C, Rattner DW, Warshaw AL (1995) Standards for pancreatic resection in the 1990s. Arch Surg 130:295–299

    Article  PubMed  CAS  Google Scholar 

  6. Cameron JL (1995) Long-term survival following pancreaticoduodenectomy for adenocarcinoma of the head of the pancreas. Surg Clin North Am 75:939–951

    PubMed  CAS  Google Scholar 

  7. Conlon KC, Dougherty E, Klimstra DS et al (1996) The value of minimal access surgery in the staging of patients with potentially resectable peripancreatic malignancy. Ann Surg 223:134–140

    Article  PubMed  CAS  Google Scholar 

  8. Catheline JM, Champault G (1996) Ultrasonic laparoscopy in digestive diseases. Ann Chir 50:51–57

    PubMed  CAS  Google Scholar 

  9. Siewert JR, Sendler A, Dittler HJ, Fink U, Hofler H (1995) Staging gastrointestinal cancer as a precondition for multimodal treatment. World J Surg 19:168–177

    Article  PubMed  CAS  Google Scholar 

  10. Conlon K, Minnard E (1997) The value of laparoscopic staging in upper gastrointestinal malignancy. The Oncologist 2:10–17

    PubMed  Google Scholar 

  11. Fernandez-del Castillo C, Warshaw AL (1993) Laparoscopy for staging in pancreatic carcinoma. Surg Oncol [Suppl 2] 1:25–29

    Article  Google Scholar 

  12. Conlon KC, Klimstra DS, Brennan MF (1996) Long-term survival after curative resection for pancreatic ductal adenocarcinoma. Clinicopathologic analysis of 5-year survivors. Ann Surg 223:273–279

    Article  PubMed  CAS  Google Scholar 

  13. de Rooj P, Rogatko A, Brennan M (1991) Evaluation of palliative surgical procedures in un-resectable pancreatic cancer. Br J Surg 78:1053–1058

    Article  Google Scholar 

  14. Watanapa P, Williamson R (1992) Surgical palliation for pancreatic cancer: Developments during the past two decades. Br J Surg 79:8–20

    Article  PubMed  CAS  Google Scholar 

  15. Warshaw AL, Tepper JE, Shipley WU (1986) Laparoscopy in the staging and planning of therapy for pancreatic cancer. Am J Surg 151:76–80

    Article  PubMed  CAS  Google Scholar 

  16. Furhman G, Charnsangavej C, Abbruzze J, Martin R, Fenoglio C, Evans D (1994) Thin-section contrast-enhanced computed tomography accurately predicts the resectability of malignant pancreatic neoplasms. Am J Surg 167:104–113

    Article  Google Scholar 

  17. Gulliver GM, Baker M, Cheng C (1992) Malignant biliary obstruction: efficacy of thin section dynamic CT scan in determining resectability. Am J Roentgenol Radium Ther Nucl Med 159:503–507

    CAS  Google Scholar 

  18. Fernandez-del CC, Warshaw AL (1998) Pancreatic cancer. Laparoscopic staging and peritoneal cytology. Surg Oncol Clin North Am 7:135–142

    Google Scholar 

  19. Burke EC, Karpeh MS, Conlon KC, Brennan MF (1997) Laparoscopy in the management of gastric adenocarcinoma. Ann Surg 225:262–267

    Article  PubMed  CAS  Google Scholar 

  20. Minnard EA, Conlon K, Hoos A, Dougherty E, Hann L, Brennan M (1998) Laparoscopic ultrasound enhances the standard laparoscopy in the staging of pancreatic cancer. Ann Surg 228:1–7

    Article  Google Scholar 

  21. John TG, Greig JD, Carter DC, Garden OJ (1995) Carcinoma of the pancreatic head and periampullary region. Tumor staging with laparoscopy and laparoscopic ultrasonography. Ann Surg 221:156–164

    Article  PubMed  CAS  Google Scholar 

  22. Holzman M, Reitgen KL, Tyler D, Pappas T (1997) The role of laparoscopy in the management of suspected pancreatic and periampullary malignancies. J Gastrointest Surg 1:236–244

    Article  PubMed  CAS  Google Scholar 

  23. Hann LE, Conlon KC, Dougherty EC, Hilton S, Bach AM, Brennan MF (1997) Laparoscopic sonography of peripancreatic tumors: preliminary experience. AJR Am J Roentgenol 169:1257–1262

    PubMed  CAS  Google Scholar 

  24. Ishida H (1983) Peritoneoscopy and pancreas biopsy in the diagnosis of pancreatic diseases. Gastrointest Endosc 29:211–218

    Article  PubMed  CAS  Google Scholar 

  25. Cuschieri A (1988) Laparoscopy for pancreatic cancer: does it benefit the patient? Eur J Surg Oncol 14:41–44

    PubMed  CAS  Google Scholar 

  26. Warshaw AL, Gu ZY, Wittenberg J, Waltman AC (1990) Preoperative staging and assessment of resectability of pancreatic cancer. Arch Surg 125:230–233

    Article  PubMed  CAS  Google Scholar 

  27. Harrison LE, Brennan MF (1998) Portal vein resection for pancreatic adenocarcinoma. Surg Oncol Clin North Am 7:165–181

    CAS  Google Scholar 

  28. Merchant N, Conlon KC (1998) Laparoscopic evaluation in pancreatic cancer. Semin Surg Oncol 15:155–165

    Article  PubMed  CAS  Google Scholar 

  29. Murugiah M, Paterson-Brown S, Windsor JA, Miles WF, Garden OJ (1993) Early experience of laparoscopic ultrasonography in the management of pancreatic carcinoma. Surg Endosc 7:177–181

    Article  PubMed  CAS  Google Scholar 

  30. Bemelman WA, de WL, van DO et al (1995) Diagnostic laparoscopy combined with laparoscopic ultrasonography in staging of cancer of the pancreatic head region. Br J Surg 82:820–824

    Article  PubMed  CAS  Google Scholar 

  31. Callery MP, Strasberg SM, Doherty GM, Soper NJ, Norton JA (1997) Staging laparoscopy with laparoscopic ultrasonography: optimizing resectability in hepatobiliary and pancreatic malignancy. J Am Coll Surg 185:33–39

    PubMed  CAS  Google Scholar 

  32. Richards A, Sosin H (1973) Cancer of the pancreas: Value of radical and palliative surgery. Ann Surg 177:325–331

    Article  PubMed  CAS  Google Scholar 

  33. Fromm D, Resitarti D, Kozol R (1988) An analysis of when patients eat after gastrojejunostomy. Ann Surg 207:14–20

    Article  PubMed  CAS  Google Scholar 

  34. Connie J, Nagpal S, Peebles S (1989) Surgical treatment for adenocarcinoma of the pancreas. Surg Gynecol Obstet 168:437–445

    Google Scholar 

  35. Blievernicht SW, Neifeld JP, Terz JJ, Lawrence W Jr (1980) The role of prophylactic gastroje-junostomy for unresectable periampullary carcinoma. Surg Gynecol Obstet 151:794–796

    PubMed  CAS  Google Scholar 

  36. Singh S, Longmire W, Reber H (1990) Surgical palliation for pancreatic cancer: The UCLA experience. Ann Surg 212:132–139

    Article  PubMed  CAS  Google Scholar 

  37. Warshaw A, Swanson R (1998) Pancreatic Cancer in 1988: Possibilities and probabilities. Ann Surg 208:541–553

    Article  Google Scholar 

  38. Potts J, Brougham T, Herman R (1990) Palliative operations for pancreatic carcinoma. Ann Surg 159:72–78

    Article  Google Scholar 

  39. Sarr M, Cameron J (1984) Surgical palliation of unresectable carcinoma of the pancreas. World J Surg 8:906–918

    Article  PubMed  CAS  Google Scholar 

  40. Meinke W, Twomey PL, Guernsey J, Frey C, Higgings G, Keehn R (1983) Gastric outlet obstruction after palliative surgery for cancer of the head of the pancreas. Arch Surg 118:550–553

    Article  PubMed  CAS  Google Scholar 

  41. Hunstad DA, Norton JA (1995) Management of pancreatic carcinoma. Surg Oncol 4:61–74

    Article  PubMed  CAS  Google Scholar 

  42. Huguier M, Baumel H, Manderscheild J, Houry S, Fabre J (1993) Surgical palliation for un-resected cancer of the exocrine pancreas. Eur J Surg Oncol 19:342–347

    PubMed  CAS  Google Scholar 

  43. van Dijkum, EJ, de Witt LT, van Delden OM et al (1997) The efficacy of laparoscopic staging in patients with upper gastrointestinal tumors. Cancer 79:1315–1319

    Article  Google Scholar 

  44. Schmassmann A, von GE, Knuchel J, Scheurer U, Fehr HF, Halter (1996) Wallstents versus plastic stents in malignant biliary obstruction: effects of stent patency of the first and second stent on patient compliance and survival. Am J Gastroenterol 91:654–659

    PubMed  CAS  Google Scholar 

  45. Vij JC, Govil A, Chaudhary A, Gulati R, Mehta S, Ganguli S (1996) Endoscopic biliary endoprosthesis for palliation of gallbladder carcinoma. Gastroint Endosc 43:121–123

    Article  CAS  Google Scholar 

  46. Eschelman D, Shapiro M, Bonn J, Sullivan KL, Alden M, Gardiner G (1996) Malignant biliary duct obstruction: Long term experience with Gianturco stents and combined modality radiotherapy. Radiology 200:717–724

    PubMed  CAS  Google Scholar 

  47. Schantz S, Schikler W, Evans T, Coffey R (1984) Palliative gastroenterostomy for pancreatic cancer. Am J Surg 147:793–796

    Article  PubMed  CAS  Google Scholar 

  48. Espat NJ, Brennan MF, Conlon KC (1999) Laparoscopically staged patients with unresectable pancreatic adenocarcinoma do not require subsequent biliary or gastric bypass. J Am Coll Surg 186:649–55

    Article  Google Scholar 

  49. Friess H, Kleef J, Silva J, Sadowski S, Baer H (1998) The role of diagnostic laparoscopy in pancreatic and periampullary malignancies. J Am Coll of Surg 186:675–682

    Article  CAS  Google Scholar 

  50. Andersen JR, Sorensen SM, Kruse A, Rokkjaer M, Matzen P (1989) Randomised trial of endoscopic endoprosthesis versus operative bypass in malignant obstructive jaundice. Gut 30:1132–1135

    Article  PubMed  CAS  Google Scholar 

  51. Sheperd H, Royle G, Ross A, Diba A, Arthur M, Colin-Jones D (1988) Endoscopic biliary endoprosthesis in the palliation of malignant obstruction of the distal common bile duct: a randomized trial. Br J Surg 75:1166–1168

    Article  Google Scholar 

  52. Shimi S, Banting S, Cuschieri A (1992) Laparoscopy in the management of pancreatic cancer: endoscopic cholecystojejunostomy for advanced disease. Br J Surg 79:317–319

    Article  PubMed  CAS  Google Scholar 

  53. Fletcher DR, Jones RM (1992) Laparoscopic cholecystjejunostomy as palliation for obstructive jaundice in inoperable carcinoma of pancreas. Surg Endosc 6:147–149

    Article  PubMed  Google Scholar 

  54. Hawasli A (1992) Laparoscopic cholecysto-jejunostomy for obstructing pancreatic cancer: technique and report of two cases. J Laparoendosc Surg 2:351–355

    Article  PubMed  CAS  Google Scholar 

  55. Wilson R, Varma J (1992) Laparoscopic gastroenterostomy for malignant duodenal obstruction. Br J Surg 79:1348–1352

    Article  PubMed  CAS  Google Scholar 

  56. JarnaginW-R, Conlon K, Bodniewicz J, Dougherty E, DeMatteo R-P, Blumgart L-H, Fong Y (2001) A clinical scoring system predicts the yield of diagnostic laparoscopy in patients with potentially resectable hepatic colorectal metastases. Cancer 91: 1121–8.

    Article  Google Scholar 

  57. Jarnagin W-R, Bodniewicz J, Dougherty E, Conlon K, Blumgart L-H, Fong Y (2000) A prospective analysis of staging laparoscopy in patients with primary and secondary he-patobiliary malignancies. J Gastrointest Surg. 4: 34–43.

    Article  PubMed  CAS  Google Scholar 

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Authors
  1. N. J. Espat
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  2. K. C. Conlon
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Editor information

Editors and Affiliations

  1. Division of Surgery and Surgical Oncology Charité, Robert-Roessle Hospital, Humboldt University, Lindenberger Weg 80, 13222, Berlin, Germany

    Peter Hohenberger

  2. Gastric & Mixed Tumor Service, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY, 10021, USA

    K. Conlon MD, MBA, FACS

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© 2002 Springer-Verlag Berlin Heidelberg

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Espat, N.J., Conlon, K.C. (2002). Laparoscopic Staging for Pancreatic Malignancy. In: Hohenberger, P., Conlon, K. (eds) Staging Laparoscopy. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-56290-7_8

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  • DOI: https://doi.org/10.1007/978-3-642-56290-7_8

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-63000-2

  • Online ISBN: 978-3-642-56290-7

  • eBook Packages: Springer Book Archive

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