Abstract
So-called chronic cerebrovascular disorders (CCVD) represent an ill-defined nosological entity which includes polymorphous clinical pictures with different pathogenesis, type and degree of morphological or functional damage, evolution and prognosis [7]. Attempts to give a better definition of this group of disorders, however, have been made during recent years for methodological reasons, particularly in the need to establish standardized admission criteria for drug trials. According to the definition commonly in use [18], patients are considered as having CCVD when meeting the following requirements:
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a)
history of one or more cerebrovascular episodes, including transient ischaemic attacks;
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b)
presence of vascular risk factors (mainly hypertension);
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c)
presence of focal or diffuse neurological and/or psychiatric signs;
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d)
positivity of instrumental examinations, such as computed tomography (CT) scan, positron emission scan or magnetic resonance imaging (MRI)
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e)
mild derangement of higher cerebral functions.
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References
American Psychiatric Association Committee on Nomenclature and Statistics (1980) Diagnostic and statistical manual of mental disorders (DSM-III), 3rd edn. American Psychiatric Association, Washington DC
Babikian V, Ropper AH (1987) Binswanger’s disease: a review. Stroke 18: 2–12
Bono G, Martelli A, Merlo P, Trucco M, Sinforiani E, Covelli V, Nappi G (1988) Binswanger’s disease: a term in need of revision? New trends in clinical neuropharmacology, 2: 263–268
Cummings JL, Miller B, Hill MA, Neshkes R (1987) Neuropsychiatrie aspects of multi-infarct dementia and dementia of the Alzheimer type. Arch Neurol 44: 389–393
Drayer BP, Heyman A, Wilkinson W, Barret L, Weinberg T (1985) Early-onset Alzheimer’s disease: an analysis of CT findings. Ann Neurol 17: 407–410
Erkinjuntti T (1988) Dementia. Clinical diagnosis and differential diagnosis, with special reference to multi-infarct dementia. Medical Faculty of the University of Helsinki, Helsinki
Fisher CM (1960) Dementia in cerebrovascular disease. Trans Am Neurol Assoc 85: 147–152
Folstein MF, Folstein SE, McHugh PR (1975) “Mini Mental State”. A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 12: 189–198
Hachinski VC, Iliff LD, Zilka E, DuBoulay GH, McAllister VL, Marshall J, Rüssel RWR, Symon L (1975) Cerebral blood flow in dementia. Arch Neurol 32: 632–637
Hachinski VC, Potter P, Merskey H (1987) Leuko-araiosis. Arch Neurol 44: 21–23
Harrison MJG, Thomas DJ, DuBoulay GH, Marshall J (1979) Multi-infarct dementia. J Neurol Sci 40: 97–103
Hershey LA, Modic MT, Jaffe DF, Greenough PG (1986) Natural history of the vascular dementias: a prospective study of seven cases. Can J Neurol Sci 13: 559–565
Hughes CP, Berg L, Danziger WL, Coben LA, Martin RL (1982) A new clinical state for the staging of dementia. Br J Psychiatry 140: 566–572
Loeb C (1980) Clinical diagnosis of multi-infarct dementia. In: Amaducci L, Davison AN, Antuono P (eds) Aging of the brain and dementia. Raven, New York, pp 251–260
Loeb C (1985) Vascular dementias. In: Frederiks JAM (ed) Handbook of clinical neurology neurobehavioural disorders, vol 2. Elsevier Science, Amsterdam, pp 353–369
Martelli A, Micieli G, Rodriguez y Baena R, Locatelli D, Bono G, Nappi G (1982) CT abnormalities of deep biemispheric white matter in cerebrovascular disorders. J Neurosurg Sci 26: 95–97
McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM (1984) Alzheimer’s disease: report of the NINCDS-ADRDA work group under the auspices of Department of Health and Human Service Task Force on Alzheimer’s Disease. Neurology 34: 939–944
SIR (ed) (1981) Drug and methods in C.V. D. Proceedings of the international Symposium on experimental and clinical methodologies for study of acute and chronic cerebrovascular diseases, 24–26 March 1980, Paris, SIR (ed) Pergamon, pp 3–14
Rogers RL, Meyer JS, Mortel KF, Mahurin RK, Judd BW (1986) Decreased cerebral blood flow procèdes multi-infarct dementia but follow senile dementia of Alzheimer type. Neurology 36: 1–6
Steingart A, Hachinski VC, Lau C, Fox AJ, Fox H, Lee D, Inzitari D, Merskey H (1987) Cognitive and neurologic findings in demented patients with diffuse white matter lucencies on computed tomographic scan (leuko-araiosis). Arch Neurol 44: 36–39
Valentine AR, Mosely IF, Kendall BE (1980) White matter abnormality in cerebral atrophy: clinico-radiological correlation. J Neurol Neurosurg Psychiatry 43: 139–142
Whitehouse PJ, Price DL, Struble RG, Clark AW, Coyle JT, De Long MR (1982) Alzheimer’s disease and senile dementia — loss of neurons in the basal forebrain. Science 215: 1237–1239
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Bono, G., Martelli, A., Merlo, P., Mauri, M., Sinforiani, E., Nappi, G. (1989). Current Problems in the Clinical Diagnosis of Vascular Dementia. In: Bergener, M., Reisberg, B. (eds) Diagnosis and Treatment of Senile Dementia. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-46658-8_9
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DOI: https://doi.org/10.1007/978-3-642-46658-8_9
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