Abstract
Orbital tumors represent approximately 0.1 % of all body tumors and approximately one-fifth of all orbital diseases. Classification schemes vary and stratify orbital tumors based on demographics, site of origin, anatomic location within the orbit, histopathologic features, clinical course, and imaging findings. Defining orbital neoplasia presents difficulties, as choristomas, hamartomas, and inflammatory lesions can present as space-occupying lesions and behave as benign and even malignant, neoplasms. In general, neoplasms of the orbit may be classified as primary, secondary (infiltration from an adjacent structure), or metastatic (from distant structures). Orbital neoplasia can be divided into histological categories that include benign, benign but locally aggressive, and malignant. In some cases, especially lymphoproliferative lesions, a spectrum from benign to malignant exists.
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References
Shields JA, Bakewell B, Augsburger JJ, Donoso LA, Bernardino V. Space-occupying orbital masses in children. A review of 250 consecutive biopsies. Ophthalmology. 1986;93:379–84.
Jakobiec FA, Ellsworth R, Tannenbaum M. Primary orbital melanoma. Am J Ophthalmol. 1974;78:24–39.
Stefanyszyn MA, Hidayat AA, Pe’er JJ, Flanagan JC. Lacrimal sac tumors. Ophthal Plast Reconstr Surg. 1994;10:169–84.
Jakobiec FA, Font RL, Zimmerman LE. Malignant peripheral nerve sheath tumors of the orbit: a clinicopathologic study of eight cases. Trans Am Ophthalmol Soc. 1985;83:332–66.
Jaeger MJ, Green WR, Miller NR, Harris GJ. Granular cell tumor of the orbit and ocular adnexa. Surv Ophthalmol. 1987;31:417–23.
Goldberg RA, Rootman J, Cline RA. Tumors metastatic to the orbit: a changing picture. Surv Ophthalmol. 1990;35:1–24.
Freedman MI, Folk JC. Metastatic tumors to the eye and orbit. Patient survival and clinical characteristics. Arch Ophthalmol. 1987;105:1215–9.
Cline RA, Rootman J. Enophthalmos: a clinical review. Ophthalmology. 1984;91:229–37.
Albert DM, Rubenstein RA, Scheie HG. Tumor metastasis to the eye. II. Clinical study in infants and children. Am J Ophthalmol. 1967;63:727–32.
Jakobiec FA, Klepach GL, Crissman JD, Spoor TC. Primary differentiated neuroblastoma of the orbit. Ophthalmology. 1987;94:255–66.
Reifler DM, Hornblass A. Squamous cell carcinoma of the eyelid. Surv Ophthalmol. 1986;30:349–65.
Howard GR, Nerad JA, Carter KD, Whitaker DC. Clinical characteristics associated with orbital invasion of cutaneous basal cell and squamous cell tumors of the eyelid. Am J Ophthalmol. 1992;113:123–33.
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© 2014 Springer-Verlag Berlin Heidelberg
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Costin, B.R., Perry, J.D., Foster, J.A. (2014). Classification of Orbital Tumors. In: Perry, J., Singh, A. (eds) Clinical Ophthalmic Oncology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-40492-4_2
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DOI: https://doi.org/10.1007/978-3-642-40492-4_2
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