The bone marrow is a mesenchymal derived tissue divided into irregular interconnective spaces by bone trabeculae. It consists of a complex haematopoietic cellular component that is extremely labile and continuously goes through self-replication and differentiation processes. These cells are supported by a micro environment composed of stromal cells (endothelial cells, fi broblast like cells, adipocytes), extracellular matrix and vascular structures.
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Further Reading
Arcesi R, Hann IM, Smith OP (2006) Paediatric haematology, 3rd edn. Blackwell Publishing, Oxford, ISBN 1-4051-3400-3/9781405134002
Hutchinson RJ (2006) Surgerical implications of hematological disease. In JL Grosfeld, JA O'Neill, AG Coran, EW Fonkalsrud (eds) Pediatric Surgery. Mosby, Philadelphia, PA, pp 178–193
Luchtman-Jones L (2005) Blood. In KT Oldham, PM Colombani, RP Foglia, MA Skinner (eds) Principles of Practice of Pediatric Surgery. Lippincott Williams & Wilkins, Philadelphia, PA, pp 297–312
Puri P, Höllwarth ME (eds) (2006) Pediatric Surgery. Springer, Berlin, Heidelberg
Shaun McCann, Robin Foa, Owen Smith, Eibhlin Conneally (2005) Case-Based Haematology. Blackwell Publishing, Oxford, ISBN 4051-1321-9
Smith OP, Hann I (2002) Essential Paediatric Haematology. Martin Dunitz Publishers, London, ISBN 90-5823-179-8
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Smith, O.P. (2009). Haematological Problems. In: Puri, P., Höllwarth, M. (eds) Pediatric Surgery. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-69560-8_9
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DOI: https://doi.org/10.1007/978-3-540-69560-8_9
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