Abstract
The cone and cone–rod dystrophies are a heterogeneous group of disorders, both in terms of clinical features and underlying genetic basis, that are a major cause of childhood blindness and arguably the most devastating of inherited retinal conditions due to the loss of central vision at an early stage. They are characterised by reduced central vision, colour vision abnormalities, visual field loss and a variable degree of nystagmus and photophobia. There is absent or severely impaired cone function on electroretinography (ERG) and psychophysical testing. Patients with cone–rod dystrophy (CORD) develop additional rod system abnormalities that lead to night blindness and peripheral visual field loss later in the disease process.
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© 2014 Springer-Verlag Berlin Heidelberg
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Michaelides, M. (2014). Cone and Cone–Rod Dystrophies. In: Puech, B., De Laey, JJ., Holder, G. (eds) Inherited Chorioretinal Dystrophies. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-69466-3_13
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DOI: https://doi.org/10.1007/978-3-540-69466-3_13
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