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Architecture of the Cell Nucleus

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Functional Ultrastructure
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Abstract

The nucleus is the largest of the cellular compartments, housing the chromosomes with the vast majority of the cellular genome, as well as multiple molecular machineries necessary for gene organisation and expression. During the past years contemporarily with the successful sequencing of the entire human genome, knowledge of nuclear architectures has also enormously increased and exciting results provide evidence that the longstanding dogma of a spatial separation of gene transcription in the nucleus and translation in the cytoplasm cannot be maintained.

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© 2010 Springer-Verlag/Wien

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Pavelka, M., Roth, J. (2010). Architecture of the Cell Nucleus. In: Functional Ultrastructure. Springer, Vienna. https://doi.org/10.1007/978-3-211-99390-3_2

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