Summary
34 patients with clinical symptomatology of disturbance in platelet turnover were investigated using In-111-labeled autologous platelets. Platelet kinetics were determined using mathematical algorithms. In HIV associated thrombocytopenia, a decreased platelet production was found together with a shortened survival of platelets. In ITP, the diminished survival was predominant, while in toxic bone marrow injury, the platelet production was compromised. Patients with vasculitis presented with enhanced platelet production.
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© 1995 Birkhäuser Verlag Basel
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Behr, T., Becker, W., Bair, HJ., Schwab, J., Wolf, F. (1995). Thrombocytopenia in HIV, Idiopathic Thrombocytopenic Purpura (ITP), Vasculitis and Toxic Bone Marrow Injury: An Etiologic Entity ? Results of a Comparative Study. In: Bergmann, H., Sinzinger, H. (eds) Radioactive Isotopes in Clinical Medicine and Research. Advances in Pharmacological Sciences. Birkhäuser Basel. https://doi.org/10.1007/978-3-0348-7340-6_7
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DOI: https://doi.org/10.1007/978-3-0348-7340-6_7
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