Skip to main content
SpringerLink
Log in

Chirurgie des tumeurs endocrines (primitif et métastases)

  • Chapter
Tumeurs endocrines thoraciques et digestives

  • 326 Accesses

Abstrait

La chirurgie est l’unique moyen de guérir les tumeurs endocrines (TE) lorsqu’elles sont diagnostiquées à un stade localisé. Elle a également une place de plus en plus importante dans les formes métastatiques, principalement hépatiques. Elle s’intègre dans une démarche globale et doit donc être systématiquement discutée en commission multidisciplinaire comprenant des spécialistes de ces tumeurs particulières. L’anesthésiste est également un partenaire obligatoire. Le plus souvent, il s’agit d’une chirurgie réalisée à visée curative ou, du moins avec l’objectif de réséquer la totalité de la maladie macroscopique tumorale décelable en préopératoire. Plus rarement, il s’agit d’une chirurgie incomplète réalisée à des fins de contrôle symptomatique.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Références

  1. Faggiano A, Ducreux M, Sabourin J et al. (2004) Les carcinomas endocrines peu différenciés à grandes cellules: modalités diagnostiques, caracteristiques cliniques et facteurs pronostiques. Gastroenterol Clin Biol 28: A170

    Google Scholar 

  2. Dromain C, de Baere T, Baudin E et al. (2003) MR imaging of hepatic metastases caused by neuro-endocrine tumors with MR: comparing four different techniques. AJR Am J Roentgenol 180: 121–8

    PubMed  Google Scholar 

  3. Modlin IM, Lye KD, Kidd M (2003) A 5-decade analysis of 13715 carcinoid tumors. Cancer 97: 934–59

    Article  PubMed  Google Scholar 

  4. Hochwald SN, Zee S, Conlon KC et al. (2002) Prognostic factors in pancreatic endocrine neoplasms: an analysis of 136 cases with a proposal for low-grade and intermediate-grade groups. J Clin Oncol 20: 2633–42

    Article  PubMed  Google Scholar 

  5. Delaunoit T, Ducreux M, Boige V et al. (2004) The doxorubicin-streptozotocin combination for the treatment of advanced well-differentiated pancreatic endocrine carcinoma: a judicious option? Eur J Cancer 40: 515–20

    Article  PubMed  CAS  Google Scholar 

  6. Weidenmann B, Jensen RT, Mignon M et al. (1998) Consensus conference. Preoperative diagnosis and surgical management of neuroendocrine gastroenteropancreatic tumors. World J Surg 22: 309–18

    Article  Google Scholar 

  7. Norton J, Fraker D, Alexander R et al. (1999) Surgery to cure the Zollinger-Ellison syndrome. N Engl J Med 341: 635–44

    Article  PubMed  CAS  Google Scholar 

  8. Norton JA, Alexander HR, Fraker DL et al. (2004) Does the use of routine duodenotomy affect rate of cure, development of liver metastases or survival in patients with Zollinger-Ellison syndrome? Ann Surg 239: 617–26

    Article  PubMed  Google Scholar 

  9. Chen H, Hardacre JM, Uzar A et al. (1998) Isolated liver metastases from neuroendocrine tumors: does resection prolong survival? J am Coll Surg 187: 88–93

    Article  PubMed  CAS  Google Scholar 

  10. Que FG, Nagorney DM, Batts KP et al. (1995) Hepatic resection for metastatic neuroendocrine carcinomas. Am J Surg 169: 36–42

    Article  PubMed  CAS  Google Scholar 

  11. Dousset B, Saint-Marc O, Pitre J et al. Metastatic endocrine tumors: medical treatment, surgical resection, or liver transplantation. World J surg 1996; 20: 908–15

    Article  PubMed  CAS  Google Scholar 

  12. Chamberlain RS, Canes D, Brown TK et al. (2000) Hepatic neuroendocrine metastases: does intervention alter outcomes, J Am Coll Surg 190: 432–45

    Article  PubMed  CAS  Google Scholar 

  13. Yao KA, Talamonti MS, Nemcek A et al. (2001) Indications and results of liver resection and hepatic chemoembolization for metastatic gastrointestinal neuroendocrine tumors. Surgery 130: 677–85

    Article  PubMed  CAS  Google Scholar 

  14. Elias D, Lasser P, Ducreux M et al. (2003) Liver resection (and associated extra-hepatic resections) for metastatic well-differenciated endocrine tumors: a 15-year single center prospective study. Surgery 133: 375–82

    Article  PubMed  Google Scholar 

  15. Elias D, Lasser PH, Debaene B et al. (1995) Intermittent vascular exclusion of the liver (without vena cava clamping) during major hepatectomy. Br J Surg 82: 1535–9

    Article  PubMed  CAS  Google Scholar 

  16. Elias D, Debaerre T, Roche A et al. (1998) Preoperative selective portal vein embolizations are effective means of extending the indications of major hepatectomy in the normal and injured liver. Hepato-Gastroenterology 45: 170–7

    PubMed  CAS  Google Scholar 

  17. Elias D, de Baere T, Muttillo I et al. (1998) Intra-operative use of radiofrequency allows an increase in the rate of curative liver resection. J Surg Oncol 67: 190–1

    Article  PubMed  CAS  Google Scholar 

  18. Elias D, El Otmany A, Goharin A et al. (2001) Intraductal cooling of the main bile ducts during intraoperative radiofrequency ablation. J Surg Oncol 30: 1–4

    Google Scholar 

  19. Ouellet JF, Pessaux P, Pocard M et al. (2002) Transmetastasis curative liver resection immediately following radiofrequency destruction. J Surg Oncol 81: 108–10

    Article  PubMed  Google Scholar 

  20. Adam R, Laurent A, Azoulay D et al. (2000) Two-stage hepatectomy: a planned strategy to treat irresectable liver tumors. Ann Surg 232: 777–85

    Article  PubMed  CAS  Google Scholar 

  21. Elias D, Ouellet JF, Baudin E (2001) Resection and radiofrequency ablation of 42 neuroendocrine liver metastases in a single patient. Int J Surg Invest 3: 453–6

    Google Scholar 

  22. Vasseur B, Cadiot G, Zins M et al. (1996) Peritoneal carcinomatosis in patients with digestive endocrine tumors. Cancer 78: 1686–92

    Article  PubMed  CAS  Google Scholar 

  23. Elias D, Sideris L, Liberale G et al. (2004) Surgical treatment of peritoneal carcinomatosis from endocrine tumours. Surgery 2004 (Submitted)

    Google Scholar 

  24. Norton JA, Alexander R, Fraker D et al. (2001) Comparison of surgical results in patients with advanced and limited disease with MEN type 1 and Zollinger-Ellison syndrome. Ann Surg 234: 495–506

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Service de chirurgie générale carcinologique, Institut Gustave-Roussy, 39, rue Camille-Desmoulins, 94805, Villejuif Cedex

    D. Elias

  2. Service de chirurgie viscérale et digestive, Institut Gustave-Roussy, 39, rue Camille-Desmoulins, 94805, Villejuif Cedex

    D. Goéré

Authors
  1. D. Elias
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. D. Goéré
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

Copyright information

© 2008 Springer-Verlag France, Paris

About this chapter

Cite this chapter

Elias, D., Goéré, D. (2008). Chirurgie des tumeurs endocrines (primitif et métastases). In: Tumeurs endocrines thoraciques et digestives. Springer, Paris. https://doi.org/10.1007/978-2-287-35574-5_14

Download citation

  • DOI: https://doi.org/10.1007/978-2-287-35574-5_14

  • Publisher Name: Springer, Paris

  • Print ISBN: 978-2-287-35573-8

  • Online ISBN: 978-2-287-35574-5

Publish with us

Policies and ethics

Search

Navigation