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Pruritus in Autoimmune Diseases

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Pruritus

Abstract

Autoimmune diseases are a collection of more than 80 individual diseases that are estimated to affect more than 3% of the U.S. population.1 Underlying this diverse group of diseases is one common pathology: the malfunction of the immune system, resulting in the destruction of self-tissue. The etiology of autoimmune diseases is thought to have both genetic and environmental contributions.

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References

  1. Jacobson DL, Gange SJ, Rose NR, Graham NM. Epidemiology and estimated population burden of selected autoimmune diseases in the United States. Clin Immunol Immunopathol. 1997;84(3):223-243.

    Article  PubMed  CAS  Google Scholar 

  2. Levy C, Lindor KD. Management of primary biliary cirrhosis. Curr Treat Options Gastroenterol. 2003;6(6):493-498.

    Article  PubMed  Google Scholar 

  3. Sigurgeirsson B, Lindelof B, Edhag O, Allander E. Risk of cancer in patients with dermatomyositis or polymyositis. A population-based study. N Engl J Med. 1992;326(6):363-367.

    Article  PubMed  CAS  Google Scholar 

  4. Chow WH, Gridley G, Mellemkjaer L, McLaughlin JK, Olsen JH, Fraumeni JF, Jr. Cancer risk following polymyositis and dermatomyositis: a nationwide cohort study in Denmark. Cancer Causes Control. 1995;6(1):9-13.

    Article  PubMed  CAS  Google Scholar 

  5. Ytterberg SR. Infectious agents associated with myopathies. Curr Opin Rheumatol. 1996;8(6):507-513.

    Article  PubMed  CAS  Google Scholar 

  6. Caro I. Dermatomyositis. Semin Cutan Med Surg. 2001;20(1):38-45.

    Article  PubMed  CAS  Google Scholar 

  7. Kurzrock R, Cohen PR. Cutaneous paraneoplastic syndromes in solid tumors. Am J Med. 1995;99(6):662-671.

    Article  PubMed  CAS  Google Scholar 

  8. Peloro TM, Miller OF, III, Hahn TF, Newman ED. Juvenile dermatomyositis: a retrospective review of a 30-year experience. J Am Acad Dermatol. 2001;45(1):28-34.

    Article  PubMed  CAS  Google Scholar 

  9. Sontheimer RD. Dermatomyositis: an overview of recent progress with emphasis on dermatologic aspects. Dermatol Clin. 2002;20(3):387-408.

    Article  PubMed  Google Scholar 

  10. Sontheimer RD. Dermatomyositis: an overview of recent progress with emphasis on dermatologic aspects. Dermatol Clin. 2002;20(3):387-408.

    Article  PubMed  Google Scholar 

  11. Shirani Z, Kucenic MJ, Carroll CL, et al. Pruritus in adult dermatomyositis. Clin Exp Dermatol. 2004;29(3):273-276.

    Article  PubMed  CAS  Google Scholar 

  12. Hundley JL, Carroll CL, Lang W, et al. Cutaneous symptoms of dermatomyositis significantly impact patients’ quality of life. J Am Acad Dermatol. 2006;54(2):217-220.

    Article  PubMed  Google Scholar 

  13. Crowson AN, Magro CM. The role of microvascular injury in the pathogenesis of cutaneous lesions of dermatomyositis. Hum Pathol. 1996;27(1):15-19.

    Article  PubMed  CAS  Google Scholar 

  14. Patel P, Werth V. Cutaneous lupus erythematosus: a review. Dermatol Clin. 2002;20(3):373-85, v.

    Article  PubMed  Google Scholar 

  15. Kapadia N, Haroon TS. Cutaneous manifestations of systemic lupus erythematosus: study from Lahore. Pakistan Int J Dermatol. 1996;35(6):408-409.

    Article  CAS  Google Scholar 

  16. Goransson LG, Brun JG, Harboe E, Mellgren SI, Omdal R. Intraepidermal nerve fiber densities in chronic inflammatory autoimmune diseases. Arch Neurol. 2006;63(10):1410-1413.

    Article  PubMed  Google Scholar 

  17. Ho KT, Reveille JD. The clinical relevance of autoantibodies in scleroderma. Arthritis Res Ther. 2003;5(2):80-93.

    Article  PubMed  CAS  Google Scholar 

  18. Cepeda EJ, Reveille JD. Autoantibodies in systemic sclerosis and fibrosing syndromes: clinical indications and relevance. Curr Opin Rheumatol. 2004;16(6):723-732.

    Article  PubMed  CAS  Google Scholar 

  19. Basu D, Reveille JD. Anti-scl-70. Autoimmunity. 2005;38(1):65-72.

    Article  PubMed  CAS  Google Scholar 

  20. Wallengren J, Akesson A, Scheja A, Sundler F. Occurrence and distribution of peptidergic nerve fibers in skin biopsies from patients with systemic sclerosis. Acta Derm Venereol. 1996;76(2):126-128.

    PubMed  CAS  Google Scholar 

  21. Meyer O. Prognostic markers for systemic sclerosis. Joint Bone Spine. 2006;73(5):490-494.

    Article  PubMed  CAS  Google Scholar 

  22. Soy M, Piskin S. Cutaneous findings in patients with primary Sjogren’s syndrome. Clin Rheumatol. 2007;26(8):1350-1352.

    Article  PubMed  Google Scholar 

  23. Provost TT, Watson R. Cutaneous manifestations of Sjogren’s syndrome. Rheum Dis Clin North Am. 1992;18(3):609-616.

    PubMed  CAS  Google Scholar 

  24. Bernacchi E, Amato L, Parodi A, et al. Sjogren’s syndrome: a retrospective review of the cutaneous features of 93 patients by the Italian Group of Immunodermatology. Clin Exp Rheumatol. 2004;22(1):55-62.

    PubMed  CAS  Google Scholar 

  25. Hertl M, Eming R, Veldman C. T cell control in autoimmune bullous skin disorders. J Clin Invest. 2006;116(5):1159-1166.

    Article  PubMed  CAS  Google Scholar 

  26. Mihai S, Sitaru C. Immunopathology and molecular diagnosis of autoimmune bullous diseases. J Cell Mol Med. 2007;11(3):462-481.

    Article  PubMed  CAS  Google Scholar 

  27. Woldegiorgis S, Swerlick RA. Pemphigus in the southeastern United States. South Med J. 2001;94(7):694-698.

    PubMed  CAS  Google Scholar 

  28. Caproni M, Feliciani C, Fuligni A, et al. Th2-like cytokine activity in dermatitis herpetiformis. Br J Dermatol. 1998;138(2):242-247.

    Article  PubMed  CAS  Google Scholar 

  29. Amerio P, Verdolini R, Giangiacomi M, et al. Expression of eotaxin, interleukin 13 and tumour necrosis factor-alpha in dermatitis herpetiformis. Br J Dermatol. 2000;143(5):974-978.

    Article  PubMed  CAS  Google Scholar 

  30. Engineer L, Bhol K, Ahmed AR. Pemphigoid gestationis: a review. Am J Obstet Gynecol. 2000;183(2):483-491.

    Article  PubMed  CAS  Google Scholar 

  31. Castro LA, Lundell RB, Krause PK, Gibson LE. Clinical experience in pemphigoid gestationis: report of 10 cases. J Am Acad Dermatol. 2006;55(5):823-828.

    Article  PubMed  Google Scholar 

  32. Chan LS, Traczyk T, Taylor TB, Eramo LR, Woodley DT, Zone JJ. Linear IgA bullous dermatosis. Characterization of a subset of patients with concurrent IgA and IgG anti-basement membrane autoantibodies. Arch Dermatol. 1995;131(12):1432-1437.

    Article  PubMed  CAS  Google Scholar 

  33. Sitaru C. Experimental models of epidermolysis bullosa acquisita. Exp Dermatol. 2007;16(6):520-531.

    Article  PubMed  CAS  Google Scholar 

  34. Pai S, Marinkovich MP. Epidermolysis bullosa: new and emerging trends. Am J Clin Dermatol. 2002;3(6):371-380.

    Article  PubMed  Google Scholar 

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Ishiuji, Y., Fleischer, A.B. (2010). Pruritus in Autoimmune Diseases. In: Misery, L., Ständer, S. (eds) Pruritus. Springer, London. https://doi.org/10.1007/978-1-84882-322-8_15

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  • DOI: https://doi.org/10.1007/978-1-84882-322-8_15

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