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Psoriatic Arthritis

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A Clinician's Pearls and Myths in Rheumatology

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Abstract

Psoriatic arthritis (PsA) is a distinctive category of inflammatory arthritis that complicates cutaneous psoriasis. The prevalence of PsA in the general population is estimated to be between 0.3% and 1%, only slightly less common than that of rheumatoid arthritis (RA). PsA is one of the “seronegative spondyloarthropa-thies”, along with ankylosing spondylitis (AS), reactive arthritis, and the arthropathy of inflammatory bowel disease. As a seronegative disorder, PsA is not associated with autoantibodies such as rheumatoid factor or antibodies to cyclic citrullinated peptides. A variety of clinical patterns of PsA are recognized: distal joint disease, oligoarthritis, a symmetrical polyarthritis that resembles RA, and spondylitis. Some patients present with combinations of these features: e.g., oligoarthritis plus spondylitis. These clinical patterns are not necessarily stable over time. For example, distal joint disease can evolve into polyarthritis. The most common pattern of joint involvement at presentation is an asymmetric oligoarthritis. This pattern accounts for about 70% of PsA cases.

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Author information

Authors and Affiliations

  1. Rheumatology Department, University of Rochester, 601 Elmwood Avenue, Box 695, Rochester, NY, 14642, USA

    Christopher Ritchlin

  2. Division of Rheumatology Boston, Brigham & Women's Hospital, Massachusetts, 02115

    Elinor Mody

  3. Seattle Rheumatology Associates, 1101 Madison Street, Suite 1000 Seattle, Washington, 98104

    Philip Mease

  4. Toronto Western Hospital, 399 Bathurst St. RM1E-4OB Toronto, Ontario, M5T 2S8, Canada

    Dafna D. Gladman

Authors
  1. Christopher Ritchlin
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  2. Elinor Mody
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  3. Philip Mease
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  4. Dafna D. Gladman
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Editor information

Editors and Affiliations

  1. Clinical Rheumatology, Massachusetts General Hospital, 55 Fruit Street / Yawkey 2, Boston, MA, 02114

    John H. Stone (Director) (Director)

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Ritchlin, C., Mody, E., Mease, P., Gladman, D.D. (2009). Psoriatic Arthritis. In: Stone, J.H. (eds) A Clinician's Pearls and Myths in Rheumatology. Springer, London. https://doi.org/10.1007/978-1-84800-934-9_8

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  • DOI: https://doi.org/10.1007/978-1-84800-934-9_8

  • Publisher Name: Springer, London

  • Print ISBN: 978-1-84800-933-2

  • Online ISBN: 978-1-84800-934-9

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