Abstract
The chapter takes into consideration the clinical manifestations, genetic patterns, histopathology, animal models, cellular immunity, circulating autoantibodies, target autoantigens, laboratory diagnostic criteria, and the therapy of the autoimmune parathyroid diseases. Much of these data satisfy the criteria for autoimmune diseases.
The mechanism of damage of the parathyroid glands in autoimmune parathyroid diseases may be related to a cell-mediated immune response against parathyroid antigens. Ca-SRAbs appear to be serological markers of the disease; however, the possible effect of the autoantibodies on the Ca-SR activity needs to be confirmed.
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Betterle, C. (2008). Autoimmune Parathyroid Disease. In: Shoenfeld, Y., Cervera, R., Gershwin, M.E. (eds) Diagnostic Criteria in Autoimmune Diseases. Humana Press. https://doi.org/10.1007/978-1-60327-285-8_49
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DOI: https://doi.org/10.1007/978-1-60327-285-8_49
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