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Abstract

The purpose of this chapter is to provide a clearer understanding of contemporary problems in the field of hereditary cancer, particularly as they relate to mortality, and with the ultimate goals of stimulating needed research and of improving patient care. This will be done both by discussing general principles that apply to all hereditary cancers and by showing specific examples. There are several previous reviews (1–4) to which the reader is referred for detailed descriptions and discussions of specific hereditary-cancer syndromes. However, because the field is changing rapidly, one of the more reliable and comprehensive sources for accurate and current information on specific hereditary-cancer syndromes is the Internet (see the Online Mendelian Inheritance in Man at http://www.hgmp.mrc.ac.uk/omim/index.html).

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Boman, B.M., Melchert, L., Fields, J.Z. (2002). Hereditary Cancer. In: Coleman, W.B., Tsongalis, G.J. (eds) The Molecular Basis of Human Cancer. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-125-1_8

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