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Cubosomes: Structure, Preparation and Use as an Antigen Delivery System

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Subunit Vaccine Delivery

Part of the book series: Advances in Delivery Science and Technology ((ADST))

Abstract

Some lipids, when dispersed in excess water can form submicron-sized particles which retain the internal microstructure of their respective parent bulk non-dispersed phase. One type of these particles possesses internally the bicontinuous cubic phase, referred to as cubosomes. Cubosomes are a versatile new drug delivery platform with potential for high loading of actives with varying physiochemical properties and the potential of sustained release. In this chapter, their application as a new platform delivery system for vaccines is reviewed, with a focus on recent data demonstrating the immunological potential of cubosomes.

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Authors and Affiliations

  1. New Zealand’s National School of Pharmacy, University of Otago, Dunedin, New Zealand

    Shakila B. Rizwan

  2. Faculty of Pharmacy and Pharmaceutical Sciences, Monash University, Melbourne, VIC, Australia

    Ben J. Boyd

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  1. Shakila B. Rizwan
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  2. Ben J. Boyd
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Correspondence to Shakila B. Rizwan .

Editor information

Editors and Affiliations

  1. Department of Pharmacy, University of Copenhagen, Faculty of Health and Medical Sciences, Copenhagen, Denmark

    Camilla Foged

  2. University of Copenhagen, Copenhagen, Denmark

    Thomas Rades

  3. Pharmacy School, Aston University, School of Life and Health Sciences, Birmingham, United Kingdom

    Yvonne Perrie

  4. Division of Health Sciences, University of Otago, School of Pharmacy, Dunedin, New Zealand

    Sarah Hook

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Rizwan, S.B., Boyd, B.J. (2015). Cubosomes: Structure, Preparation and Use as an Antigen Delivery System. In: Foged, C., Rades, T., Perrie, Y., Hook, S. (eds) Subunit Vaccine Delivery. Advances in Delivery Science and Technology. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-1417-3_7

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