Abstract
Peripheral nerves serve as communication links between the central nervous system and the rest of the body. Once a nerve is severed, the functions innervated by it are lost. From the severed ends nearest the spinal cord the nerves sprout new growth in a process that, if successful, leads to reconnection. Without any guidance, these sproutings rarely reconnect and quickly die. Regeneration of the severed nerve into its distal section is the objective of all attempts to return function to the extremeties.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Further reading
Lundborg G (1987): Nerve regeneration and repair: A review. Acta Orthop Scand 58:145–69
Madison R (1985): Increased rate of peripheral nerve regeneration using bioresorbable nerve guides and a laminin-containing gel. Exp Neurol 88:767–72
Varon S (1978): Trophic mechanisms in the peripheral nervous system. Annu Rev Neurosci 1:327–61
Yannas IV (1990): Biologically active analogs of the extracellular matrix. Angewandte Chemie 29:20–35
Frost JJ, Wagner HN Jr. (1990): Quantitative Imaging: Neuroreceptors, Neurotransmitters, and Enzymes, New York: Raven Press,
Phelps ME, Mazziotta JC (1985): PET: Human brain function and biochemistry. Science 228:799–809
Phelps ME, Mazziotta JC, Schelbert HR (1986): Positron Emission Tomography and Autoradiography: Application in the Brain and Heart, New York: Raven Press
Allen HL, Iversen LL (1990): Phencyclidine, dizocilpine, and cerebrocortical neurons: Technical comments. Science 247:221
Labruyere J, Price MT, Olney JW (1989): NMDA antagonists induce pathomorphological changes in cerebrocortical neurons. Neurosci Abst 15:761
Olney JW (1989): Excitatory amino acids and neuropsychiatric disorders. Biol Psychiatry 26:505–525
Olney JW, Labruyere J, Price MT (1989): Pathological changes induced in cerebrocortical neurons by phencyclidine and related drugs. Science 244:1360–1362
Olney JW, Labruyere J, Wang GJ, Price MT (1990): Anticholinergics prevent neurotoxic side effects of NMDA antagonists. Neurosci Abst 16:1122
Trends in Neuroscience (1987): Special issue: Excitatory amino acids in the brain—focus on NMDA receptors. 10:263–302
Musen G, Treisman A (1990): Implicit and explicit memory for visual patterns. J Exp Psychol 16:127–137
Richardson-Klavehn A, Bjork RA (1988): Measures of memory. Annu Rev Psychol 36: 475–543
Roediger HL, Weldon MS, Challis B (1989): Explaining dissociations between implicit and explicit measures of retention: A processing account. In: Varieties of memory and consciousness: Essays in honor of Ende) Tulving, Roediger HL, Craik FIM, eds. Hillsdale, NJ: Lawrence Erlbaum Associates
Schacter DL (1987): Implicit memory: history and current status, J Exp Psychol 13: 501–518
Schacter DL (1990): Perceptual representation systems and implicit memory: Toward a resolution of the multiple memory debate. In: Development and Neural Basis of Higher Cognitive Function. Diamond A, ed. New York Academy of Sciences, 608:543–571
Squire LR (1987): Memory and Brain. New York: Oxford University Press
Tulving E, Schacter DL (1990): Priming and human memory systems, Science 247:301–306
Weiskrantz L (1987): Neuroanatomy of memory and amnesia: A case for multiple memory systems. Human Neurobiol 6:93–105
Editor information
Rights and permissions
Copyright information
© 1992 Springer Science+Business Media New York
About this chapter
Cite this chapter
Chang, A.S., Yannas, I.V., Wagner, H.N., Olney, J.W., Tulving, E., Schacter, D.L. (1992). P. In: Smith, B., Adelman, G. (eds) Neuroscience Year. Supplement Encyclopedia of Neuroscience. Birkhäuser, Boston, MA. https://doi.org/10.1007/978-1-4899-6754-1_13
Download citation
DOI: https://doi.org/10.1007/978-1-4899-6754-1_13
Publisher Name: Birkhäuser, Boston, MA
Print ISBN: 978-1-4899-6756-5
Online ISBN: 978-1-4899-6754-1
eBook Packages: Springer Book Archive