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Nutrition

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Multiple Sclerosis

Part of the book series: Therapy in Practice Series ((TPS,volume 18))

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Abstract

The role of nutrition in the management of multiple sclerosis (MS) is often neglected despite evidence implicating nutritional factors in the aetiology of the disease (see Chapter 2). In addition, studies of the food intake of people with MS have been shown to be low in energy, zinc, copper, folate, calcium and B vitamins (Witschi et al., 1970; Crawford and Stevens, 1981; Harding and Crawford, 1981; Hewson et al., 1984). The provision of nutritional advice to people with a chronic disease such as MS is likely to prevent nutrient deficiencies occurring. It would seem sensible to suggest an increase in the nutrients which are involved in the support and maintenance of the central nervous system (CNS).

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References

  • Agranoff, B. and Goldberg, D. (1974) Diet and the geographical distribution of multiple sclerosis. Lancet, 11, 1061–6.

    Article  Google Scholar 

  • Allison, R. (1963) Some neurological aspects of medical geography. Proceedings of the Royal Society of Medicine, 56, 71–6.

    PubMed  CAS  Google Scholar 

  • Baker, R., Thompson, R. and Zilkha, K. (1964) Serum fatty acids and multiple sclerosis. Journal of Neurology, Neurosurgery and Psychiatry, 27, 408–14.

    Article  CAS  Google Scholar 

  • Bates, D., Fawcett, P.R.W., Shaw, D.A. et al. (1978) Polyunsaturated fatty acids in the treatment of acute remitting multiple sclerosis. British Medical Journal, 2, 1390–1.

    Article  PubMed  CAS  Google Scholar 

  • Bates, D., Belin, J., Cartlidge, N.E.F. et al. (1989) A double-blind controlled trial of long chain n-3 polyunsaturated fatty acids in the treatment of multiple sclerosis. Journal of Neurology, Neurosurgery and Psychiatry, 52, 18–22.

    Article  CAS  Google Scholar 

  • Bernsohn, J. and Stephanides, L.M. (1967) Aetiology of multiple sclerosis. Nature (London), 215, 821.

    CAS  Google Scholar 

  • Cherayil, G.D. (1984) Sialic acid and fatty acid concentrations in lymphocytes, red blood cells, and plasma from patients with multiple sclerosis. Journal of Neurological Sciences, 63, 1–10.

    Article  CAS  Google Scholar 

  • Crawford, M.A., Hassam, A., Williams, G. et al. (1976) Essential fatty acids and foetal brain growth. Lancet, 1, 452.

    Article  PubMed  CAS  Google Scholar 

  • Crawford, M.A., Budowski, P. and Hassam, A.G. (1979) Dietary management in multiple sclerosis. Proceedings of the Nutrition Society, 38, 373–89.

    Article  PubMed  CAS  Google Scholar 

  • Crawford, M.A. and Stevens, P. (1981) A study on essential fatty acids and multiple sclerosis. Progress in Lipid Research, 20, 255–7.

    Article  PubMed  CAS  Google Scholar 

  • DHSS (1984) Diet and cardiovascular disease. Committee on Medical Aspects (COMA) of Food Policy, Report on Health and Social Subjects No. 28. HMSO, London.

    Google Scholar 

  • Dick, G. (1976) The aetiology of multiple sclerosis. Proceedings of the Royal Society of Medicine, 69, 611–16.

    PubMed  CAS  Google Scholar 

  • Dworkin, R.H., Bates, D., Millar, J.H.D. et al. (1984) Linoleic acid and multiple sclerosis: a re-analysis of three double blind trials. Neurology, 34, 1441–5.

    Article  PubMed  CAS  Google Scholar 

  • Fitzgerald, G.E., Simpson, K.E., Harbige, L.S. et al. (1987) The effect of nutritional counselling on dietary compliance and disease course in multiple sclerosis patients over three years, in Multiple Sclerosis: Immunological, Diagnostic and Therapeutic Aspects, Current problems in Neurology No.3. Chap. 26, (eds F. Clifford Rose and R. Jones ). John Libbey Pubs.Co., London and Paris, pp. 189–99.

    Google Scholar 

  • Greer, R. (1982) Diets to Help Multiple Sclerosis. Thorsons, Northants

    Google Scholar 

  • Gul, S., Smith, A.D., Thompson, R.H.S. et al. (1970) Fatty acid composition of phospholipids from platelets and erythrocytes in multiple sclerosis. Journal of Neurology, Neurosurgery and Psychiatry, 33, 506–10.

    Article  CAS  Google Scholar 

  • Gupta, J., Ingengno, A., Cook, A. et al. (1977) Multiple sclerosis and malabsorption. American Journal of Gastroenterology, 68, 560.

    PubMed  CAS  Google Scholar 

  • Gurr, M.I. (1983) The role of lipids in the regulation of the immune system. Progress in Lipid Research, 22, 257–87.

    Article  PubMed  CAS  Google Scholar 

  • Harding, J. and Crawford, M.A. (1981) The role of diet in multiple sclerosis. Applied Nutrition, 1 (BDA Study Conference), 20–3.

    Google Scholar 

  • Hewson, D.C. (1984) Is there a role for gluten-free diets in multiple sclerosis? Human Nutrition: Applied Nutrition, 38A, 417–20.

    PubMed  CAS  Google Scholar 

  • Hewson, D.C., Phillips, M.A., Simpson, K.E. et al. (1984) Food intake in multiple sclerosis. Human Nutrition: Applied Nutrition, 30A, 355–67.

    Google Scholar 

  • Houtomuller, U.M.T. (1975) Specific biological effects of polyunsaturated fatty acids, in The Role of Fats in Human Nutrition, (ed. A.J. Vergroessen ). Academic Press, London, pp. 331–51.

    Google Scholar 

  • Lange, L.S. and Shiner, H. (1976) Small bowel abnormalities in multiple sclerosis. Lancet, 11, 1319–22.

    Article  Google Scholar 

  • Lessof, M.H. (1986) Allergy and its mechanisms. British Medical Journal, 292, 385–7.

    Article  PubMed  CAS  Google Scholar 

  • Liversedge, L.A. (1977) Treatment and management of multiple sclerosis. British Medical Bulletin, 33, 78–83.

    PubMed  CAS  Google Scholar 

  • McDougall, R. (1989) My Fight Against Multiple Sclerosis. Regenics Pubn., Chorley, Lancs.

    Google Scholar 

  • Millar, J.H.D., Zilkha, K.S., Langman, M.J.S. et al. (1973) Double blind trial of linoleate supplementation of the diet in multiple sclerosis. British Medical Journal, 1, 765–8.

    Article  PubMed  CAS  Google Scholar 

  • NACNE (1983) A discussion paper on proposals for nutritional guidelines for health education in Britain. The National Advisory Committee on Nutrition: Education Working Party chaired by Prof. W.P.T. James. Health Education Council Publication, London.

    Google Scholar 

  • Neu, I.S. (1983) Essential fatty acids in the serum and cerebrospinal fluid of multiple sclerosis patients. Acta Neurologica Scandinavica, 67, 151–63.

    Article  PubMed  CAS  Google Scholar 

  • Paty, D.W., Cousin, H.K., Read, S. et al. (1978) Linoleic acid in multiple sclerosis: failure to show any therapeutic benefit. Acta Neurologica Scandinavica, 58, 53–8.

    Article  PubMed  CAS  Google Scholar 

  • Sanders, H., Thompson, R.H.S., Wright, H.P. et al. (1968) Further studies on platelet adhesiveness and serum cholesteryl linoleate levels in multiple sclerosis. Journal of Neurology, Neurosurgery and Psychiatry, 31, 321–5.

    Article  CAS  Google Scholar 

  • Shatin, R. (1964) Multiple sclerosis and geography: new interpretation of epidemiological observations. Neurology (Minneap.), 14, 338.

    Article  CAS  Google Scholar 

  • Simpson, K.E. and Hewson, D. (1985) Food intake in multiple sclerosis. Proceedings of the 2nd International Congress on EFAs, PGs and Leukotrienes. The Zoological Society of London, March.

    Google Scholar 

  • Sinclair, H. (1956) Deficiency of essential fatty acids and atherosclerosis. Lancet, 1, 381.

    Google Scholar 

  • Srivastava, K.C., Foc, T. and Clausen, J. (1975) The synthesis of prostaglandins in platelets from patients with multiple sclerosis. Acta Neurologica Scandinavica, 51, 193–9.

    Article  CAS  Google Scholar 

  • Swank, R.L. (1950) Multiple sclerosis: a correlation of its incidence with dietary fat. American Journal of Medical Science, 220, 441–50.

    Google Scholar 

  • Swank, R.L. (1970) Multiple sclerosis: 20 years on a low-fat diet. Archives of Neurology, 23, 460–74.

    Article  PubMed  CAS  Google Scholar 

  • Swank, R.L. and Duggan, B.B. (1987) The Multiple Sclerosis Diet Book: A low fat diet for the treatment of MS. Doubleday and Co.Inc., New York.

    Google Scholar 

  • Thompson, R.H.S. (1966) A biochemical approach to the problem of multiple sclerosis. Proceedings of the Royal Society of Medicine, 59, 269–76.

    PubMed  CAS  Google Scholar 

  • Thompson, R.H.S. (1975) Unsaturated fatty acids in multiple sclerosis, in Multiple Sclerosis Research (eds A.N. Davison, J.H. Humphry, A.L. Liversedge et al.) USA: Elsevier, North Holland, pp. 184–93.

    Google Scholar 

  • Tsang, N., Smith, A., Weyman, C. et al. (1976) Immunosuppression by fatty acids. Lancet, 11, 254.

    Google Scholar 

  • Wright, H.P., Thompson, R.H.S. and Zilkha, K.J. (1965) Platelet adhesiveness in multiple sclerosis. Lancet, 11, 1109–10.

    Article  Google Scholar 

  • Witschi, J.C., Littell, A.S., Houser, H.B. et al. (1970) Dietary intake of non-hospitalized persons with multiple sclerosis. Journal of American Dietetic Association, 56, 203–11.

    Google Scholar 

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© 1990 Lorraine De Souza

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Fitzgerald, G. (1990). Nutrition. In: Multiple Sclerosis. Therapy in Practice Series, vol 18. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-3107-8_8

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  • DOI: https://doi.org/10.1007/978-1-4899-3107-8_8

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-0-412-32230-3

  • Online ISBN: 978-1-4899-3107-8

  • eBook Packages: Springer Book Archive

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