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Effect of Lithium on the Thyroid Gland

  • Chapter
Endocrine and Metabolic Effects of Lithium

Abstract

Although lithium therapy for manic-depressive psychosis was suggested in 1949, not until 1967 was it realized that lithium might have an effect on the thyroid gland. In that year, a symposium on lithium and goiter was held at Risskov, Denmark. In the following year, Schou et al.1 reported the occurrence of goiter in patients on lithium treatment and concluded that there was a causal relationship between goiter and lithium therapy. During the following years, a large volume of basic and clinical research has been performed to establish the pathophysiology of the action of lithium on the thyroid gland. The clinical relevance of the effects of lithium in patients receiving lithium therapy and patients with thyroid disease has also been assessed. Useful reviews of the effect of lithium on thyroid function have been published.2–4

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Authors and Affiliations

  1. University of Wales College of Medicine, Cardiff, Wales, UK

    John H. Lazarus M.D., F.R.C.P.

  2. University College Cardiff, Cardiff, Wales, UK

    Keith J. Collard Ph.D.

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  1. John H. Lazarus M.D., F.R.C.P.
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© 1986 Springer Science+Business Media New York

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Lazarus, J.H., Collard, K.J. (1986). Effect of Lithium on the Thyroid Gland. In: Endocrine and Metabolic Effects of Lithium. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-2016-4_5

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  • DOI: https://doi.org/10.1007/978-1-4899-2016-4_5

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