Abstract
Goiter and hypothyroidism due to iodine deficiency are major world health problem. Intake of excess iodine, either in food, water or drugs, may also result in disturbances of thyroid function and goiter1,2. Clinical data as well as animal experiences have shown a sharp rise in the incidence of autoimmune thyroiditis when iodine consumption was increased. 2,3,4 Administration of iodine or or iodine containing drugs increases the incidence of thyroid autoantibodies in humans without illness as well as in populations with endemic goiter. 5,6,7 Hokkaido is located in the northernmost part of Japan. Separated from the main island by the sea, Hokkaido covers an area of 83,511Km2, and its population of 5. 3 million is considerably lower than that of the rest of Japan.
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© 1993 Springer Science+Business Media New York
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Matsuura, N., Harada, S. (1993). Iodine Excess and Thyroid Autoimmunity. In: Delange, F., Dunn, J.T., Glinoer, D. (eds) Iodine Deficiency in Europe. NATO ASI Series, vol 241. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-1245-9_10
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DOI: https://doi.org/10.1007/978-1-4899-1245-9_10
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