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Part of the book series: Cancer Treatment and Research ((CTAR,volume 65))

Abstract

Melanoma is curable when detected early, with 5-year survival ranging from 93% to 100% when Breslow thickness at the time of excision is less than 0.76mm [1]. Prognosis worsens with increasing thickness, though, and even with advances in melanoma awareness many melanomas are detected too late: 5-year mortality from localized melanoma (American Joint Committee on Cancer Stages I and II) ranges from 15% to 35% in different centers [1].

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References

  1. Balch CM, Cascinelli N, Drzewiecki KT, Eldh G, MacKie RM, McCarthy WH, et al. 1992. A comparison of prognostic figures worldwide. In CM Balch, AN Houghton, GW Milton, AJ Sober, S Soong (eds), Cutaneous Melanoma, 2nd ed. Philadelphia: JB Lippincott, p. 194.

    Google Scholar 

  2. Fitzpatrick TB, Milton GW, Balch CM, Shaw HM, McCarthy WH, Sober AJ. 1992. Clinical characteristics. In CM Balch, AN Houghton, GW Milton, AJ Sober, S Soong (eds), Cutaneous Melanoma, 2nd ed. Philadelphia: JB Lippincott, pp 229–230.

    Google Scholar 

  3. Friedman RJ, Rigel DS. 1985. The clinical features of malignant melanoma. Dermatol Clin 3:271–283.

    PubMed  CAS  Google Scholar 

  4. McGovern TW, Litaker MS. 1991. Clinical predictors of malignant pigmented lesions. A comparison of the Glasgow seven-point checklist and the American Cancer Society’s ABCDs of pigmented lesions. J Dermatol Surg Oncol. 18:22–26.

    Google Scholar 

  5. Koh HK. 1991. Cutaneous melanoma. N Engl J Med 325:171–182.

    Article  PubMed  CAS  Google Scholar 

  6. Ho VC, Milton GW, Sober AJ. 1992. Biopsy of melanoma. In CM Balch, AN Houghton, GW Milton, AJ Sober, S Soong (eds), Cutaneous Melanoma, 2nd ed. Philadelphia: JB Lippincott, pp 265–268.

    Google Scholar 

  7. Andersen WK, Silvers DN. 1991. Melanoma? It can’t be melanoma! A subset of melanomas that defies clinical recognition. JAMA 266:3463–3465.

    Article  PubMed  CAS  Google Scholar 

  8. Grossman DJ. 1989. Public and professional educational materials on skin cancer. J Am Acad Dermatol 21:1012–1018.

    Article  PubMed  CAS  Google Scholar 

  9. Hennrikus D, Girgis A, Redman S, Sanson-Fisher RW. 1991. A community study of delay in presenting with signs of melanoma to medical practitioners. Arch Dermatol 127:356–361.

    Article  PubMed  CAS  Google Scholar 

  10. Koh HK, Lew RA, Prout MN. 1989. Screening for melanoma/skin cancer: Theoretic and practical considerations. J Am Acad Dermatol 20:159–172.

    Article  PubMed  CAS  Google Scholar 

  11. Koh HK, Caruso A, Gage I, Geller AC, Prout MN, White H, O’Connor K, Balash EM, Blumenthal G, Rex IH JR, et al. 1990. Evaluation of melanoma/skin cancer screening in Massachusetts. Preliminary results. Cancer 15:375–379.

    Article  Google Scholar 

  12. Koh HK, Geller AC, Miller DM, Caruso A, Gage I, Lew RA. 1991. Who is being screened for melanoma/skin cancer? Characteristics of persons screened in Massachusetts. J Am Acad Dermatol 24:271–277.

    Article  PubMed  CAS  Google Scholar 

  13. Lee G, Massa MC, Welykyj S, Choo J, Greaney V. 1991. Yield from total skin examination and effectiveness of skin cancer awareness program. Findings in 874 new dermatology patients. Cancer 67:202–205.

    Article  PubMed  CAS  Google Scholar 

  14. Lookingbill DP. 1988. Yield from a complete skin examination: Findings in 1157 new dermatology patients. J Am Acad Dermatol 18:31–37.

    Article  PubMed  CAS  Google Scholar 

  15. Rhodes AR, Weinstock MA, Fitzpatrick TB, Mihm MC Jr, Sober AJ. 1987. Risk factors for cutaneous melanoma. A practical method of recognizing predisposed individuals. JAMA 258:3146–3154.

    Article  PubMed  CAS  Google Scholar 

  16. MacKie RM, Freudenberger T, Aitchison TC. 1989. Personal risk-factor chart for cutaneous melanoma. Lancet 2:487–490.

    Article  PubMed  CAS  Google Scholar 

  17. Cohen MH, Cohen BJ, Shotkin JD, Morrision PT. 1991. Surgical prophylaxis of malignant melanoma. Ann Surg 213:308–314.

    Article  PubMed  CAS  Google Scholar 

  18. Kraemer KH, Greene MH, Tarone R, Elder DE, Clark WH Jr, Guerry D 4th. 1983. Dysplastic nevi and cutaneous melanoma risk (letter). Lancet 2:1076–1077.

    Article  PubMed  CAS  Google Scholar 

  19. Barnes LM, Nordlund JJ. 1987. The natural history of dysplastic nevi. A case history illustrating their evolution. Arch Dermatol 123:1059–1061.

    Article  PubMed  CAS  Google Scholar 

  20. Bergman W, Palan A, Went LN. 1986. Clinical and genetic studies in six Dutch kindreds with the dysplastic nevus syndrome. Ann Hum Genet 50:249–258.

    Article  PubMed  CAS  Google Scholar 

  21. Bale SJ, Chakravarti A, Greene MH. 1986. Cutaneous malignant melanoma and familial dyspastic nevi: Evidence for autosomal dominance and pleiotropy. Am J Hum Genet 38:188–196.

    PubMed  CAS  Google Scholar 

  22. Greene MH, Clark WH Jr, Tucker MA, Kraemer KH, Elder DE, Fraser MC. 1985. High risk of malignant melanoma in melanoma-prone patients with dysplastic nevi. Ann Intern Med 102:458–465.

    PubMed  CAS  Google Scholar 

  23. Halpern AC, Guerry D 4th, Elder DE, Clark WH Jr, Synnestvedt M, Norman S, Ayerle R. 1991. Dysplastic nevi as risk factors of sporadic (nonfamilial) melanoma. A case-control study. Arch Dermatol 127:995–999.

    Article  PubMed  CAS  Google Scholar 

  24. Geller AC, Koh HK, Miller DR, Lew RA. 1992. Practices and beliefs concerning screening family members of patients with melanoma. Results of a survey of New England dermatologists. J Am Acad Dermatol 26:419–422.

    Article  PubMed  CAS  Google Scholar 

  25. Crijns MB, Vink J, Van Hees CL, Bergman W, Vermeer BJ. 1991. Dysplastic nevi. Occurrence in first-and second-degree relatives of patients with’ sporadic’ dysplastic nevus syndrome. Arch Dermatol 127:1346–1351.

    Article  PubMed  CAS  Google Scholar 

  26. Albert LS, Rhodes AR, Sober AJ. 1990. Dysplastic melanocytic nevi and cutaneous melanoma: Markers of increased melanoma risk for affected persons and blood relatives. J Am Acad Dermatol 22:69–75.

    Article  PubMed  CAS  Google Scholar 

  27. Tiesten AD, Grin CM, Kopf AW, Gottlieb GJ, Bart RS, Rigel DS, Friedman RJ, Levenstein MJ. 1991. Prospective follow-up for malignant melanoma in patients with atypical-mole (dysplastic-nevus) syndrome. J Dermatol Surg Oncol 17:44–48.

    Google Scholar 

  28. Masri GD, Clark WH Jr, Guerry D 4th, Halpern A, Thompson CJ, Elder DE. 1990. Screening and surveillance of patients at high risk for malignant melanoma result in detection of earlier disease. J Am Acad Dermatol 22:1042–1048.

    Article  PubMed  CAS  Google Scholar 

  29. Vasen HFA, Bergman W, Van Haeringen A, Scheffer E, Van Slooten EA. 1989. The familial dysplastic nevus syndrome. Natural history and the impact of screening on prognosis. A study of nine families in the Netherlands. Eur J Cancer Clin Oncol 25:337–341.

    Article  PubMed  CAS  Google Scholar 

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© 1993 Springer Science+Business Media New York

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Albert, L.S., Sober, A.J. (1993). Early detection of melanoma. In: Nathanson, L. (eds) Current Research and Clinical Management of Melanoma. Cancer Treatment and Research, vol 65. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3080-0_3

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  • DOI: https://doi.org/10.1007/978-1-4615-3080-0_3

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-6345-3

  • Online ISBN: 978-1-4615-3080-0

  • eBook Packages: Springer Book Archive

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