Abstract
The concept of competence and potency of the female gamete is introduced. Oocyte ability to give rise to the different cell type (potency) constituting an adult organism is discussed assessing the recent derivation of uniparental pluripotent cells. The consequence of using oocyte as a source of stem cells is examined. In this line, the impact of asymmetric imprinting and the occurrence of abnormal spindle formation in mammalian parthenotes are analyzed. The possibility to obtain oocytes from pluripotent cells is also described.
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Brevini, T.A.L., Pennarossa, G. (2013). Stem cells and Gametogenesis. In: Gametogenesis, Early Embryo Development and Stem Cell Derivation. SpringerBriefs in Stem Cells. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-5532-5_3
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DOI: https://doi.org/10.1007/978-1-4614-5532-5_3
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Publisher Name: Springer, New York, NY
Print ISBN: 978-1-4614-5531-8
Online ISBN: 978-1-4614-5532-5
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