Abstract
Dermatomyositis is an inflammatory myopathy associated with a variety of skin manifestations, has an association to malignancy, and usually presents with symmetric proximal muscle weakness. The manifestations vary dramatically between patients. Here, we present two challenging cases of amyopathic dermatomyositis and anti-synthetase syndrome.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Bendewald MJ, Wetter DA, Li X, Davis MD. Incidence of dermatomyositis and clinically amyopathic dermatomyositis: a population-based study in Olmsted County, Minnesota. Arch Dermatol. 2010;146(1):26–30.
Bohan A, Peter J. Polymyositis and dermatomyositis (first of two parts). New Engl J Med. 1975;292(7):344–7.
Bohan A, Peter J. Polymyositis and dermatomyositis (second of two parts). New Engl J Med. 1975;292(8):403–7.
Hoogendijk J, Amato A, Lecky B, Choy E, Lundberg I, Rose M, et al. 119th ENMC international workshop: trial design in adult idiopathic inflammatory myopathies, with the exception of inclusion body myositis, 10–12 Oct 2003, Naarden, The Netherlands. Neuromuscular Disorders. 2004 2003;14(5):337.
Kissel J, Mendell J, Rammohan K. Microvascular deposition of complement membrane attack complex in dermatomyositis. New Engl J Med. 1986;314(6):329.
Gerami P, Schope JM, McDonald L, Walling HW, Sontheimer RD. A systematic review of adult-onset clinically amyopathic dermatomyositis (dermatomyositis sine myositis): a missing link within the spectrum of the idiopathic inflammatory myopathies. J Am Acad Dermatol. 2006;54(4):597–613.
Marie I. Morbidity and mortality in adult polymyositis and dermatomyositis. Curr Rheumatol Rep. 2012; Jun; 14(3): 275–85
Rider L, Lachenbruch P, Monroe J, Ravelli A, Cabalar I, Feldman B, et al. Damage extent and predictors in adult and juvenile dermatomyositis and polymyositis as determined with the myositis damage index. Arthritis Rheum. 2009;60(11):4325–35.
Schiopu E, Phillips K, Macdonald P, Crofford L, Somers E. Predictors of survival in a cohort of patients with polymyositis and dermatomyositis: effect of corticosteroids, methotrexate and azathioprine. Arthritis Res Ther. 2012;14(1):R22.
Marie I, Mouthon L. Therapy of polymyositis and dermatomyositis. Autoimmun Rev. 2011;11(1):6–13.
Oddis C, Reed A, Aggarwal R, Ascherman D, Barohn R, Feldman B et al. Rituximab in the treatment of refractory adult and juvenile dermatomyositis (DM) and adult polymyositis (PM)—the RIM study. Arthritis RRS. 2010; 62 suppl. 12:3844
Katzap E, Barilla-LaBarca M, Marder G. Antisynthetase syndrome. Curr Rheumatol Rep. 2011;13(3):175–81.
Imbert-Masseau A, Hamidou M, Agard C, Grolleau J, Chérin P. Antisynthetase syndrome. Joint Bone Spine: Revue du Rhumatisme. 2003;70(3):161–8.
Richards T, Eggebeen A, Gibson K, Yousem S, Fuhrman C, Gochuico B, et al. Characterization and peripheral blood biomarker assessment of anti-Jo-1 antibody-positive interstitial lung disease. Arthritis Rheum. 2009;60(7):2183–92.
Marie I, Dominique S, Janvresse A, Levesque H, Menard J. Rituximab therapy for refractory interstitial lung disease related to antisynthetase syndrome. Respir Med. 2012;106(4):581–7.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2013 Springer Science+Business Media, LLC
About this chapter
Cite this chapter
Schiopu, E., Gladue, H. (2013). Dermatomyositis. In: Mahmoudi, M. (eds) Challenging Cases in Rheumatology and Diseases of the Immune System. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-5088-7_10
Download citation
DOI: https://doi.org/10.1007/978-1-4614-5088-7_10
Published:
Publisher Name: Springer, New York, NY
Print ISBN: 978-1-4614-5087-0
Online ISBN: 978-1-4614-5088-7
eBook Packages: MedicineMedicine (R0)