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Abdominal Complications

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Emergencies in Pediatric Oncology

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Abstract

The gastrointestinal system is often a target of toxicity of chemotherapy due to its natural pattern of rapid cell division. Different treatment modalities such as chemotherapy, radiation, and surgery as well as underlying disease processes are known to alter the mucosal surface and lead to life-threatening complications. Mucosal injury and destruction increase permeability of the mucosal barrier and lead to edema, inflammation, and bacterial invasion. Consequently, it may trigger intestinal perforation, peritonitis, sepsis, and death.

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Author information

Authors and Affiliations

  1. Division of Hematology/Oncology, McMaster Children’s Hospital, 1280 Main Street West, Hamilton, ON, Canada, L8S 4K1

    Hanna Tseitlin

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  1. Hanna Tseitlin
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Correspondence to Hanna Tseitlin .

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Editors and Affiliations

  1. Department of Pediatrics, McMaster Children’s Hospital, Division of Hematology/ Oncology, Main Street W 1200, Hamilton, L8N 3Z5, Ontario, Canada

    Katrin Scheinemann

  2. The Hospital for Sick Children, Division of Hematology/Oncology, University Ave 555, Toronto, M5G 1X8, Ontario, Canada

    Allison E. Boyce

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Tseitlin, H. (2012). Abdominal Complications. In: Scheinemann, K., Boyce, A. (eds) Emergencies in Pediatric Oncology. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-1174-1_15

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  • DOI: https://doi.org/10.1007/978-1-4614-1174-1_15

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  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4614-1173-4

  • Online ISBN: 978-1-4614-1174-1

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